Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: no test data just read-across

Data source

Referenceopen allclose all

Reference Type:
other: QSAR
Title:
Unnamed
Year:
2012
Reference Type:
study report
Title:
Unnamed
Year:
1989
Report date:
1989

Materials and methods

Test guideline
Qualifier:
no guideline followed
Guideline:
other: read-across
GLP compliance:
no
Test type:
other: read-across

Test material

Constituent 1
Reference substance name:
methyltio 2-(acetyloxy) propionate
IUPAC Name:
methyltio 2-(acetyloxy) propionate
Constituent 2
Reference substance name:
methyltio 2(propionyloxy) propionate
IUPAC Name:
methyltio 2(propionyloxy) propionate

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
1 006 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
Toxicity Category IV
Remarks:
Migrated information H302 Criteria used for interpretation of results: EU
Conclusions:
Predicted oral LD50 value in the rat 1006 mg/kg
Executive summary:

Predicted oral LD50 value in the rat 1006 mg/kg