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EC number: 430-970-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.1 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 1 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.01 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 100 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 42.04 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 4.2 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 8.32 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
The PNEC derivation was as follows justified:
PNEC freshwater sediment:
K_(susp-water) = 105.1
RHO_(susp) = 1150
Conversion factor (wwt -> dwt): 4.6
PNEC_freshwater sediment
= (K_(susp-water) / RHO_(susp)) * PNEC_water * 1000
= (105.1/1150) * 0.1 * 1000
= 9.14 mg/kg wwt
= 42.04 mg/kg dw
PNEC marine water sediment:
K_(susp-water) = 105.1
RHO_(susp) = 1150
Conversion factor (wwt -> dwt): 4.6
PNEC_marine water sediment
= (K_(susp-water) / RHO_(susp)) * PNEC_marine water * 1000
= (105.1/1150) * 0.01 * 1000
= 0.914 mg/kg wwt
= 4.204 mg/kg dw
PNEC soil:
K_(soil-water) = 125.2
RHO_(soil) = 1700
Conversion factor (wwt -> dwt): 1.13
PNEC_soil
= (K_(soil-water) / RHO_(soil)) * PNEC_freshwater * 1000
= (125.2/1700) * 0.1 * 1000
= 7.365 mg/kg wwt
= 8.32 mg/kg dw
Conclusion on classification
Acute aquatic toxicity:
96 h, LC50 (Danio rerio): >100 mg/L (nominal concentration)
48 h, EC50 (Daphnia magna): >100 mg/L (nominal concentration)
72 h, ErC50 (Desmodesmus subspicatus): >100 mg/L (nominal concentration)
Aquatic chronic toxicity:
72 h, NOEC (Desmodesmus subspicatus): ≥100 mg/L (nominal concentration)
Biodegradation: not readily biodegradable: 14.25 % after 28 days (% degradation O2 consumption, OECD 301 F)
Partition coefficient: log Kow > 5 at 20 °C
Classification according to CLP
The available experimental test data are reliable and suitable for classification purposes under Regulation (EC) No 1272/2008. The test substance was found to be not biodegradable under the test conditions. In all aquatic tests the test item showed no toxic effect on the tested species up to the limit test concentration of 100 mg/L. The determined EC50 and NOEC for Daphnia magna and green algae were >100 mg/L. The LC50 to fish was determined to be >100 mg/L. Based on these results, the substance is not classified for short-term (acute) aquatic toxicity. As Urea is poorly soluble in water, has a log Kow of >5 and is not readily biodegradable it needs to be classified for long-term (chronic) aquatic toxicity in Category 4 (H413) according to Regulation (EC) No 1272/2008 (CLP), as amended for the eighteenth time in Regulation (EU) 2022/692.
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