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EC number: 212-736-1 | CAS number: 865-33-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- potassium methanolate
- Type of composition:
- legal entity composition of the substance
- State / form:
- solid: bulk
- Reference substance:
- potassium methanolate
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Data for the definitive conclusion on the PBT or vPvB properties of potassium methanolate are not available. Thus, the screening criteria given in the “Guidance on information requirements and chemical safety assessment, chapter R.11: PBT assessment” (ECHA, 2017) are used as surrogate information to decide whether the substance may potentially fulfil the PBT or vPvB criteria. In water, potassium methanolate rapidly hydrolyses to methanol and potassium hydroxide (OECD, 2002). Due to the rapid hydrolysis of potassium methanolate, the PBT/vPvB-assessment is based on the products of hydrolysis i.e. methanol and potassium hydroxide.
Persistence
The screening criterion for persistence is the potential of a substance for degradation. The substance potassium methanolate reacts readily with water to form potassium hydroxide and methanol. Methanol is readily biodegradable whereas potassium hydroxide as an inorganic substance is no subject to biodegradation. Hence, potassium methanolate does not fulfil the criteria for persistence.
Bioaccumulation
A test on bioconcentration in aquatic organisms is not needed due to the very low potential for bioaccumulation of potassium methanolate. The substance reacts readily with water to form potassium hydroxide and methanol.
The available experimentally observed BCF values for methanol are <10 L/kg. According to “Guidance on information requirements and chemical safety assessment, chapter R.11: PBT assessment” (ECHA, 2017), the screening criterion for bioaccumulative substances which have to be classified as “B” or “vB”, is a BCF > 2000 L/kg. As the BCF for the surrogate of potassium methanolate is well below this trigger, the substance is not considered to have bioaccumulative properties in the frame of a PBT assessment.Toxicity
The screening for the “T” in support of the PBT assessment is based on acute toxicity tests with aquatic organisms.
The substance potassium methanolate reacts readily with water to form potassium hydroxide and methanol.
Low toxicity was observed in all organisms with LC50 values >100 mg/L for all endpoints (with methanol). Further, in an early-life-stage bioassay conducted with Oryzias latipes by Gonzales-Doncel et al. (2008), NOEC values for methanol between 7900 - 15800 mg/L were determined. This result indicates that methanol has a very low long-term toxicity to fish. Toxic effects of the hydrolysis product potassium hydroxide are not expected.Potassium hydroxide further dissociates in the environment to potassium (K+) and hydroxyl ions (OH-). Potassium belongs to the alkali metals and is one of the most common elements in the earth crust. Together with sodium ions (Na+), potassium ions (K+) are responsible for maintaining the cell membrane potential and essential for the function of all living cells (Clausen&Poulsen, 2013). Many physiological processes in organisms are driven by the influence of potassium. Thus, potassium ions are not considered being relevant for aquatic toxicity.
Since the endpoint of methanol is well above the trigger of 0.01 mg/L, potassium methanolate is not classified as toxic (“T”) related to the environment. The substance is not classified as carcinogenic, mutagenic or toxic for reproduction nor is there any evidence of chronic toxicity according to Regulation (EC) No 1272/2008. Therefore, potassium methanolate does not meet the T-criterion.In conclusion, the substance is not PBT/vPvB.
Reference
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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