Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Study period:
13 Sept 2012
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable method for pigments with low solubilities

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2012

Materials and methods

Principles of method if other than guideline:
Calculation of log Pow from the solubility in octanol (see section 4.9) and the solubility in water (see section 4.8 ).
Type of method:
other: calculation
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Analytical method:
other: The analytical methods for the underlying data are given in section 4.8 and 4.9

Results and discussion

Partition coefficientopen allclose all
Type:
Pow
Partition coefficient:
1 146
Temp.:
22.5 °C
pH:
ca. 6
Type:
log Pow
Partition coefficient:
3.1
Temp.:
22.5 °C
pH:
ca. 6
Details on results:
See below

Any other information on results incl. tables

At room temperature (22-23 °C), the solubility in octanol was determined to be 14900 µg/L (section 4.9) and the solubility in water was determined to be 13 µg/L (section 4.8), both at an average temperature of 22.5 °C and a pH of ca. 6 (see section 4.8). With the equation given above, the following values were calculated:

Pow = 14900 µg/L / 13 µg/L

Pow = 1146

log Pow = 3.1

Applicant's summary and conclusion

Conclusions:
The test substance has a log Pow of 3.1.
Executive summary:

The log Pow of the test substance was calculated from the solubilities in water and in octanol. The log Pow at 22.5 °C is 3.1.