Registration Dossier

Administrative data

Description of key information

Assessment of decamethylenediamine concerning skin or eye irritation is not possible because no data are available for these toxicological endpoints. Data waiver are claimed.
Assessment of decamethylenediamine concerning respiratory irritation is also not possible because no data are available for this toxicological endpoint.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no study available

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for selection of skin irritation / corrosion endpoint:
According to REACH Annex VIII 8.1.1. column 2 an in vivo skin irritation study does not need to be conducted if the substance is classified as corrosive to the skin.

Justification for selection of eye irritation endpoint:
According to REACH Annex VIII 8.2.1. column 2 an in vivo eye irritation study does not need to be conducted if the substance is classified as corrosive to the skin.

Justification for classification or non-classification

Based on the chemical structure (aliphatic diamine) and due to the fact that decamethylenediamine is a strong base (pH = 12) the substance is classified into Skin Corr. Category 1B (H314: Causes severe skin burns and eye damage) according to EC Regulation 1272/2008.