Registration Dossier
Registration Dossier
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EC number: 203-931-2 | CAS number: 112-05-0
Endpoint summary
Administrative data
Description of key information
Relevant information is given in the respective endpoint summaries.
For an overview on essential data available, please see below.
Additional information
Short-term toxicity to fish:
Fathead minnow (P. promelas): 96-h LC50 = 104 mg/L (similar to OECD TG 203, flow-through, measured; Brooke et al., 1984)
Long-term toxicity to fish:
No data available.
According to Annex IX of Regulation (EC) No 1907/2006 (Section 9.1, column 2), long-term toxicity testing shall be proposed by the registrant if the chemical safety assessment according to Annex I indicates the need to investigate further the effects on aquatic organisms. The results of the environmental exposure assessment indicate that all RCR <1; accordingly, there is no need for further testing.
Short-term toxicity to aquatic invertebrates:
Water flea (Daphnia magna): 48 -h EC50: 96 mg/L (static; mean measured; EPA OPP 72 -2; OPP, 2000)
Long-term toxicity to aquatic invertebrates:
No data available.
According to Annex IX of Regulation (EC) No 1907/2006 (Section 9.1, column 2), long-term toxicity testing shall be proposed by the registrant if the chemical safety assessment according to Annex I indicates the need to investigate further the effects on aquatic organisms. The results of the environmental exposure assessment indicate that all RCR <1; accordingly, there is no need for further testing.
Growth inhibition to aquatic algae:
In a valid study on freshwater algae growth inhibition performed compliant with GLP according to OECD 201 (Fraunhofer, 2020) the following results were obtained for the test item n-nonanoic acid:
NOEC (Raphidocelis subcapitata; 72 h; growth rate & yield; nominal, anal. verified) = 5.66 mg/L;
ErC50 (Raphidocelis subcapitata; 72 h; growth rate; nominal, anal. verified) = 25 mg/L (95% C.I.: 17.7-36.0);
ECy10 (Raphidocelis subcapitata; 72 h; yield; nominal, anal. verified) = 6.22 mg/L (95% C.I.: 4.83-8.02);
ECy50 (Raphidocelis subcapitata; 72 h; yield; nominal, anal. verified) = 8.50 mg/L (95% C.I.: 6.49-11.24).
All validity criteria of the guideline were met.
Toxicity to microorganisms:
STP microorganism toxicity was assessed based on a growth inhibition test on the ciliate Tetrahymena pyriformis (Schultz, 2006): EC50 (40 h; cell density)= 71 mg/L.
This is supported from data on ready biodegradability (OECD 301B; Celanese, 1999) - the substance was identified to be readily biodegradable, no inhibitory effects of n-nonanoic acid to sewage sludge bacteria was observed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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