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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

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Description of key information

A calculated value is available: logKow = -0.16. 
In order to test the applicability of the model for the substance of interest and so to validate the model for aminoacids, logKow of other aminoacids have been calculated using the EPIWIN program (KowWin v1.67 fragment description) and compared with the experimental data reported in the same model.
The results are as follows :
For 6 aminohexanoic acid (60-32-2): logKow (estimated) = - 2.62 logKow (experimental) : -2.95
For 8-aminooctanoic acid (1002-57-9): logKow (estimated) = -1.64 Experimental logKow = - 2,55
The estimated logKow values are similar to the experimental data reported in the same model, showing that the model is applicable to this type of aminoacids.

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20 °C

Additional information

As the applicability of the EPIWIN program (KowWin v1.67) for the estimation of log Kow values of aminoacids has been demonstrated, this calculated value is considered acceptable and its reliability is considered as "2".

Considering the log Kow value of -0.16, 11-aminoundecanoic acid has a low potential for bioaccumulation.

According to the Guidance on information requirements and chemical safety assessment Chapter R.7a: Endpoint specific guidance (ECHA, 2008), the impact of errors on model predictions for a logKow value below 1 is usually less critical. Moreover, the value estimated is outside the applicability range of the reverse phase HPLC method (OECD GL 117) and very closed to the lowest value of the applicability range of the shake flask method (OECD GL 107). Therefore, it is considered that an experimental study is not needed.