Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
ECB
Year:
2000
Bibliographic source:
Iuclid4 data set, 18/02/2000

Materials and methods

Test guideline
Guideline:
other: no data
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Trimethyl orthoformate
EC Number:
205-745-7
EC Name:
Trimethyl orthoformate
Cas Number:
149-73-5
Molecular formula:
C4H10O3
IUPAC Name:
trimethoxymethane

Test animals

Species:
rat
Strain:
other: ChR-CD
Sex:
male

Administration / exposure

Route of administration:
oral: gavage

Results and discussion

Effect levelsopen allclose all
Sex:
male
Dose descriptor:
other: acute lethal dose
Effect level:
5 000 mg/kg bw
Based on:
test mat.
Sex:
not specified
Dose descriptor:
LD50
Effect level:
3 130 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion