Registration Dossier

Administrative data

Description of key information

The test substance, Dust, steelmaking, was tested for subacute toxicity using the EU method B.7. Repeated Dose (28-days) Toxicity (Oral); the test was performed according to GLP rules.

Key value for chemical safety assessment

Repeated dose toxicity: via oral route - systemic effects

Endpoint conclusion
Dose descriptor:
NOAEL
300 mg/kg bw/day
Study duration:
subacute
Species:
rat

Additional information

No Observed Adverse Effect Level:

NOAEL = 300 mg/kg/day (rat males/females, oral, 28 d) (established on the basis of haematology and biochemistry examination)

 


Repeated dose toxicity: via oral route - systemic effects (target organ) cardiovascular / hematological: other

Justification for classification or non-classification

According to results of test of Repeated dose (28 days) Toxicity (Oral) the test item do not fulfil criteria and does not need to be classified as specific target organ toxicants following repeated exposure.