Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 600-715-3 | CAS number: 106092-09-5
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 03.11.1994 to 10.11.1994
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 995
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- checked and confirmed
- IUPAC Name:
- checked and confirmed
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- Himalayan
Test system
- Type of coverage:
- other: occlusive and semi.occlusive
- Preparation of test site:
- shaved
- Vehicle:
- physiological saline
- Controls:
- no
- Duration of treatment / exposure:
- 4 hours
- Observation period:
- 1 week
- Number of animals:
- 2 male and 2 female
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- other: cumulative irritation index
- Basis:
- animal #1
- Time point:
- other: 1 hour to 1 week
- Score:
- 0
- Max. score:
- 0
- Reversibility:
- no data
- Irritation parameter:
- other: cumulative irritation index
- Basis:
- animal #2
- Time point:
- other: 1 hour to 1 week
- Score:
- 0
- Max. score:
- 0
- Reversibility:
- no data
- Irritation parameter:
- other: cumulative irritation index
- Basis:
- animal #3
- Time point:
- other: 1 hour to 1 week
- Score:
- 0
- Max. score:
- 0
- Reversibility:
- no data
- Irritation parameter:
- other: cumulative irritation index
- Basis:
- animal #4
- Time point:
- other: 1 hour to 1 week
- Score:
- 0
- Max. score:
- 0
- Reversibility:
- no data
- Irritant / corrosive response data:
- No changes were observed on the skin of all 4 rabbits.
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: OECD GHS
- Conclusions:
- Sunstance is not dermal irritating.
- Executive summary:
On the baasis of the criteria of assessment of skin irritancy employed in this study, SND 919 CL2 Y Precursor 2 (SND 855 BS Y) was evaluated as having no irritant potential.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
