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Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
18-12-2012 to 3-01-2013
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2013

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: shake-flask method
Principles of method if other than guideline:
Determination of ratio of concentrations of a compound in the two phases of a mixture of Octanol-Water at equilibrium
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid
Details on test material:
-Substance Name: ethyl 4,4,4-trifluoroacetoacetate
-Molecular formula : C6H7F3O3
-Substance type: Organic
-physical state-liquid

Results and discussion

Partition coefficient
Type:
Pow
Partition coefficient:
1.11
Temp.:
21 °C
pH:
5.09
Remarks on result:
other: Relatively hydrophobic
Details on results:
Converting the above Pow value into its Log value, the Log Pow of ethyl 4,4,4-trifluoroacetoacetate is 0.04532297878666 at temperature 21degC and pH of 5.09.

Applicant's summary and conclusion

Conclusions:
The experimental value of octanol water partition co-efficient (log Pow) of ethyl 4,4,4-trifluoroacetoacetate is 0.04532297878666 at 21degC and pH of 5.09.
Executive summary:

The experimental value of octanol water partition co-efficient (log Pow) of ethyl 4,4,4-trifluoroacetoacetate is 0.04532297878666 at 21degC and pH of 5.09.This value indicates that ethyl 4,4,4-trifluoroacetoacetate is relatively hydrophilic in nature.