Registration Dossier

Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
18-12-2012 to 3-01-2013
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report Date:
2013

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other:
Principles of method if other than guideline:
Measurement of capacity of a compound to dissociate into respective ions.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid
Details on test material:
-Substance Name: ethyl 4,4,4-trifluoroacetoacetate
-Molecular formula : C6H7F3O3
-Substance type: Organic
-physical state-liquid

Results and discussion

Dissociating properties:
yes
Dissosciation constantopen allclose all
No.:
#1
pKa:
0
Temp.:
21 °C
Remarks on result:
other: 0.000000045 (0.450 x 10-7)
No.:
#2
pKa:
0
Temp.:
21 °C
Remarks on result:
other: 0.0000000451(0.451x 10-7)
No.:
#3
pKa:
0
Temp.:
21 °C
Remarks on result:
other: 0.0000000451 (0.451x 10-7)

Applicant's summary and conclusion

Conclusions:
The average pKa value for ethyl 4,4,4-trifluoroacetoacetate was found to be 0.0000000450666667 at 21 degC indicating that it has dissociation properties.
Executive summary:

The average pKa value for ethyl 4,4,4-trifluoroacetoacetate was found to be 0.0000000450666667 at 21 degC indicating that it has dissociation properties.