Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:
Migrated from Short description of key information:
No experimental data is available for "Acetophenone fraction" (CAS No. 101316-44-3). Phenol and acetophenone account for approximately 70 to > 80 % of the mixture. Local skin effects are expected to be determined by either constituent. Neither phenol nor acetophenone were found to be sensitisers.

Justification for selection of skin sensitisation endpoint:
No data is available for "Acetophenone fraction" (CAS No. 101316-44-3).

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:
Migrated from Short description of key information:
No experimental data is available for "Acetophenone fraction" (CAS No. 101316-44-3). Phenol and acetophenone account for approximately 70 to > 80 % of the mixture. The mixture is classified as "corrosive". Hence, no study is required for this endpoint.

Justification for selection of respiratory sensitisation endpoint:
No data is available for "Acetophenone fraction" (CAS No. 101316-44-3).

Justification for classification or non-classification

"Acetophenone fraction" (CAS No. 101316-44-3) is assumed to exhibit no skin-sensitising potential, based on negative experimental

results obtained with the key constituents, phenol and acetophenone, accounting for approximately 70 to > 80 % of the mixture. Furthermore, the mixture is classified as "corrosive". Hence, no study on the mixture itself is indicated for this endpoint, since the mixture is sufficiently classified for hazards arising from skin contact.