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Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
07/2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
Deviations:
no
GLP compliance:
no
Type of method:
microscopic examination
Type of particle tested:
agglomerate
Type of distribution:
counted distribution

Test material

Constituent 1
Chemical structure
Reference substance name:
1,3-dihydroxyacetone
EC Number:
202-494-5
EC Name:
1,3-dihydroxyacetone
Cas Number:
96-26-4
Molecular formula:
C3H6O3
IUPAC Name:
1,3-dihydroxyacetone
Details on test material:
DHA

Results and discussion

Particle sizeopen allclose all
Percentile:
D50
Mean:
> 2 - < 5 µm
Remarks on result:
not measured/tested
Remarks:
SD was not measured
Percentile:
other: Mean Size length
Mean:
7 µm
St. dev.:
5.9
Percentile:
other: Mean size diameter
Mean:
4 µm
St. dev.:
3.6
Particle size distribution at different passages
Remarks on result:
not determinable because of methodological limitations

Applicant's summary and conclusion

Conclusions:
The majority of particles have a diameter between 2 µm and 5 µm, at a length between 2,5 µm and 10 µm.
Executive summary:

The particle size distribution of DHA was investigated in an OECD guideline 110 compliant study.

No diameters < 1.3 µm were measured. The majority of particles have a diameter between 2 and 5 µm. The majority of particles have a length between 2.5 µm and 10 µm. No length 2.5 µm were measured.