Registration Dossier
Registration Dossier
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EC number: 218-878-0 | CAS number: 2272-11-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The 72-h EC50 value and the 72-h NOEC for monoethanolamine in Pseudokirchneriella subcapitata are 2.5 and 1 mg/L respectively, after correction for molecular weight the effect concentrations of 14.1 and 5.62 mg/L for monoethanolamine oleate will be used in the assessment.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 14.1 mg/L
- EC50 for marine water algae:
- 5.62 mg/L
Additional information
No long-term studies with algae are available for monoethanolamine oleate. A GLP-compliant OECD 201 test with Pseudokirchneriella subcapitata is available for one of its starting materials,monoethanolamine (NITE, 1996b). Monoethanolamine oleate is the salt of monoethanolamine and oleic acid. As oleic acid is exempted for registration according to Annex V of REACH Directive 2006/121/EC, the focus is only on the monoethanolammmonium cation of monoethanolamine oleate (for more details see reporting format for the analogue approach in Appendix A.2).
The72-h EC50 value and the 72-h NOEC for monoethanolamine are 2.5 and 1 mg/L respectively, a safety factor need not to be applied to these values. Instead, the effect concentration will be corrected for molecular weight. The effect concentrations of 14.1 and 5.62 mg/L for monoethanolamine oleate will be used in the assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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