Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Dermal absorption

Currently viewing:

Administrative data

Endpoint:
dermal absorption in vivo
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 98-42-0
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-EPI Suite (DERMWIN) Various versions of EPI Suite dating back from 1990-2004.

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modelling Database
Principles of method if other than guideline:
EPI Suite (DERMWIN)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-amino-4-methoxybenzenesulphonic acid
EC Number:
202-667-5
EC Name:
3-amino-4-methoxybenzenesulphonic acid
Cas Number:
98-42-0
Molecular formula:
C7H9NO4S
IUPAC Name:
3-amino-4-methoxybenzenesulfonic acid
Radiolabelling:
not specified

Test animals

Species:
other: no data
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified

Results and discussion

Percutaneous absorption
Remarks on result:
other: Dermal absorption value : 0.00015 mg/cm2/event (VERY LOW).

Applicant's summary and conclusion

Conclusions:
Dermal absorption value of 3-amino-4-methoxybenzenesulphonic acid is estimated to be 0.00015 mg/cm2/event (VERY LOW).
Executive summary:

Dermal absorption value of 3-amino-4-methoxy benzene sulphonic acid is estimated to be 0.00015 mg/cm2/event (VERY LOW).