Registration Dossier
Registration Dossier
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EC number: 254-384-1 | CAS number: 39255-32-8
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Examination of Ethyl 2-Methylpentanoate for Mutagenic Activity in the Ames Test: Ethyl 2-methylpentanoate did not show mutagenic activity in Salmonella typhimurium TA 1535, TA 1537, TA 1538, TA 98 and TA 100, either in the absence or in the presence of the S-9 mix, under the conditions employed in this evaluation.
In vitro mammalian cell gene forward mutation test at the hgprt locus of the Chinese hamster ovary (CHO)-K1 cell line using Ethyl 2-methylvalerate (ethyl 2-methypentanoate): From these results, it is concluded that ethyl 2-methylvalerate (ethyl 2-methylpentanoate) does not have potential to induce gene mutations at the hgprt locus of CHO-K1 cells both in the absence and presence of metabolic activation under the present experimental conditions.
In vitro mammalian chromosome aberration test of ethyl 2-methylvalerate (Ethyl 2-methylpentanoate) in human peripheral blood lymphocytes: From the results of this study, it is concluded that ethyl 2-methylvalerate (ethyl 2-methypentanoate) did not show any potential to induce chromosomal aberrations, both in the absence and presence (2 and 4% v/v S9) of metabolic activation under the present experimental conditions.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
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