Registration Dossier
Registration Dossier
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A mixture of: 4-(2,2,3-trimethylcyclopent-3-en-1-yl)-1-methyl-2-oxabicyclo[2.2.2]octane; 1-(2,2,3-trimethylcyclopent-3-en-1-yl)-5-methyl-6-oxabicyclo[3.2.1]octane; spiro[cyclohex-3-en-1-yl-[(4,5,6,6a-tetrahydro-3,6',6',6'a-tetramethyl)-1,3'(3'aH)-[2H]cyclopenta[b]furan]; spiro[cyclohex-3-en-1-yl-[4,5,6,6a-tetrahydro-4,6',6',6'a-tetramethyl)-1,3'(3'aH)-[2H]cyclopenta[b]]furan]
EC number: 422-040-1 | CAS number: 426218-78-2 CASSIFFIX
Endpoint summary
Administrative data
Description of key information
The log Koc of Cassiffix was determined using the HPLC method according to OECD TG 121. Cassiffix consists of four main constituents and of each the log Koc was determined: 4.02, 4.12, 4.19. 4.25. The weighted average value of all 4 constituents (5, 55, 20 and 20%, respectively) were used to derive the log Koc for Cassiffix of 4.2.
The Henry's law constant is calculated using the equation from EUSES. Using a molecular weight of 234.2 g/mole, and the experimentally determined vapour pressure of 1.5 Pa (at 25 °C) and water solubility of 11.1 mg/L (at 20 °C), the Henry's Law constant at 25°C and at environmental temperature (12°C) is calculated to be 29.5 and 14.1 Pa·m³/mol, respectively. The substance is expected to volatilise from water to some extent (in the OECD TG 309 ca 40% was volatilised).
Based on Level III environmental distribution modelling using EPISUITE (assuming equal and continuous releases to air, water and soil) using the SMILES code (CC3=CCC(C12CCC(C)(CC1)OC2)C3(C)C) and the measured physico-chemical parameters (water solubility (11.9 mg/l at 25 °C) and log Kow 4.72) as input, it is estimated that the majority of the substance released to the environment will partition mainly into soil (89.1%), less to water (7.2%) and sediment (3.7%) and minimally to air (<0.1%).
The SimpleTreat model, which is incorporated in EUSES simulates the distribution of the substance in a Sewage Treatment Plant based on vapour pressure, water solubility, log Koc and ready biodegradability. Model calculations show that 0% of the substance will be degraded, and that 61%, 32.2%, and 6.6% will partition to sludge, water and air, respectively.
Additional information
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