Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: guidance followed, no GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report Date:
2010

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
ca. 4.04
Temp.:
30 °C
pH:
>= 5 - <= 8
Remarks on result:
other: high purity acenapthene
Details on results:
Standard deviation: 0.10
Average Partition Coefficient (n-octanol/water): 4.04 +- 0.10

Any other information on results incl. tables

Mobile phase [Acetonitrile:water]

Retention time [min.]

log P

(interpolated)

1:1

10.49

4.16

3:2

5.90

3.97

2:3

23.75

3.99

Applicant's summary and conclusion