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EC number: 215-136-8 | CAS number: 1304-85-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 18 January 2010 to 29 January 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted in accordance with EU and OECD guidelines and in compliance with GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- See below
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- See below
- Principles of method if other than guideline:
- Deviation from the Guideline: Deionised water was used for the determination of the solubility in water of Bismuth hydroxide nitrate oxide, instead of doubly distilled water, as the validation showed, that the usage of deionised water was acceptable for the determination of the solubility in water of Bismuth compounds. This is considered as uncritical concerning the outcome of the study.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Water solubility:
- 900.7 mg/L
- Temp.:
- 20 °C
- Remarks on result:
- other: Standard deviation of all samples was 113.8 mg/L
- Details on results:
- All replicates showed very good correspondence. Standard deviation of all samples was 113.8 mg/L, corresponding to a relative standard deviation of 12.8%.
Equilibration time can be considered as < 24 hours, as the values which were measured on consecutive days did not give significantly different values.
Accuracy measurements via standard addition showed a correlation of 0.995, indicating that no matrix effects were present.
No observations arousing doubts concerning the accuracy of the results and the validity of the study were made. - Conclusions:
- Interpretation of results (migrated information): moderately soluble (100-1000 mg/L)
Using the flask method, at the plateau, the concentration of Bismuth subnitrate in water had reached 900.7 ±113.8 mg/L at 20 ± 0.5 °C (mean value ± standard deviation of six individual vessels) - Executive summary:
In a pre-test, solubility was believed to lie below 10 mg/L. Therefore, the column elution method was employed. The results of the measurements of the fractions showed, though, that solubility was far above 10 mg/L. The experiment was aborted, and solubility was determined using the flask method. The results of the column elution method are not reported.
For the flask method, 11000 - 13000 mg/L were weighed into each of six individual vessels, water was added, and the vessels were shaken at 20 ± 1.7 °C.
On the days 1, 2, and 3, vessel 1 was taken from the shaking apparatus and stored at 20 ± 0.5 °C for equilibration. Samples were taken, centrifuged or filtrated and analysed using AAS as shaking of the test vessels was continued.
No differences above 15% in the concentration of the solution could be determined between the sampling dates 1, 2, and 3, supporting the hypothesis, that the maximum concentration of the test item had been reached. Therefore, on day 3, vessels 2-5 were sampled and analysed in the same fashion.
At the plateau, the concentration of Bismuth subnitrate in water had reached 900.7 ±113.8 mg/L at 20 ± 0.5 °C (mean value ± standard deviation of six individual vessels)
Reference
Measurements during Equilibration
The data which was acquired during equilibration is presented in the following table:
Day |
Flask |
Temperature in °C |
pH |
Dilution factor |
Bi Concentration in mg/L |
Difference to previous sample |
1 |
1 |
20 |
3 |
1010 |
0.620 |
- |
2 |
1 |
20 |
3 |
1010 |
0.650 |
+ 4.8% |
3 |
1 |
20 |
3 |
1010 |
0.605 |
- 7.0 % |
Measurements at Plateau
The following table gives the values which were measured at the plateau:
Flask |
2 |
3 |
4 |
5 |
6 |
pH |
2.78 |
2.68 |
2.68 |
2.77 |
2.60 |
Concentration Bi in mg/L (diluted sample) |
0.768 |
0.654 |
0.511 |
0.718 |
0.573 |
Dilution factor |
1010 |
1010 |
1010 |
1010 |
1010 |
Concentration Bi in mg/L (original sample) |
775.6 |
660.9 |
516.4 |
724.9 |
578.4 |
Factor (Bi/test item) |
0.41471 |
0.41471 |
0.41471 |
0.41471 |
0.41471 |
Concentration test item in mg/L |
1085.2 |
924.7 |
722.5 |
1014.3 |
809.3 |
Day |
Mean Conc. (mg/L) |
Total Mean (mg/L) |
Total Stand. Dev. |
1 |
876.5 |
900.7 mg/L |
113.8 mg/L (12.8%) |
2 |
918.9 |
||
3 |
854.6 |
||
3 |
1085.2 |
||
3 |
924.7 |
||
3 |
722.5 |
||
3 |
1014.3 |
||
3 |
809.3 |
Description of key information
The water solubility of bismuth subnitrate is 900.7 mg/L.
Key value for chemical safety assessment
- Water solubility:
- 900.7 mg/L
- at the temperature of:
- 20 °C
Additional information
A study was conducted to determine the water solubility of bismuth subnitrate in accordance with OECD Guideline 105 and EU Method A.6.
Using the flask method, at the plateau, the concentration of bismuth subnitrate in water had reached 900.7 ±113.8 mg/L at 20 ± 0.5 °C (mean value ± standard deviation of six individual vessels)
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