Registration Dossier
Registration Dossier
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EC number: 201-920-7 | CAS number: 89-58-7
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Principles of method if other than guideline:
- No details on method available
- GLP compliance:
- not specified
- Test type:
- acute toxic class method
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Route of administration:
- oral: unspecified
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 2 440 mg/kg bw
Reference
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 440 mg/kg bw
Additional information
Justification for classification or non-classification
For the target substance only one value for acute oral toxicity has been reported. In analogy to other isomeric nitroxylenes it can be predicted that the 2 -nitro-p-xylene has a low toxicity. From the datas available it can not be excluded, that the substance could cause cyanosis, like many other nitroaromatic compounds do. Therefore a precautionary classification as harmful in all three application routes seems to be justified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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