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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Prehled Prumyslove Toxikologie; Organicke Latky
Author:
Marhold, J.
Year:
1986
Bibliographic source:
Czechoslovakia, Avicenum, Prague 1986, Vol. -, Pg. 420, 1986.
Reference Type:
secondary source
Title:
No information
Author:
Database
Year:
2012
Bibliographic source:
Gestis-Database of Institut für Arbeitsschutz der deutschen gesetzlichen Unfallversicherungen

Materials and methods

Principles of method if other than guideline:
No details on method available
GLP compliance:
not specified
Test type:
acute toxic class method

Test material

Constituent 1
Chemical structure
Reference substance name:
2-nitro-p-xylene
EC Number:
201-920-7
EC Name:
2-nitro-p-xylene
Cas Number:
89-58-7
Molecular formula:
C8H9NO2
IUPAC Name:
1,4-dimethyl-2-nitrobenzene

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
2 440 mg/kg bw

Applicant's summary and conclusion