Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 446-540-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Emergency measure - Inhalation: Remove to fresh air. If not breathing - give artificial
respiration.
Emergency measure - Eyes: Immediately flush eyes with copious amounts of water for at
least 15 minutes.
Emergency measure - Skin: Immediately wash skin with soap and copious amounts of
water.
Emergency measure - Ingestion: Provided person is conscious - wash out mouth with water.
Call a physician immediately.
Fire-fighting measures
Recommended extinguishing agent: Water spray, dry chemical powder, carbon dioxide,
appropriate foam.
Product arising from burning: Toxic fumes of carbon dioxide, carbon monoxide and nitrogen
oxides.
Product determined by test: N
Protective equipment: Use self contained breathing apparatus and full body
protective equipment.
Accidental release measures
Emergency measures in case of spillage: In the event of spillage (open handling) - evacuate area.
Clean up personnel should wear NIOSH approved respirator,
chemical resistant gloves and rubber boots. Sweep up spill
ensuring to avoid dust generation, and place in clean, dry
containers for disposal (incineration). Once material spill
has been collected - wash spill site with water, taking care
to keep out of sewers & drains.
Handling and storage
Handling: Avoid contact and inhalation of dust. Operate in areas
provided with efficient local exhaust ventilation systems.
All dispensing, sampling and charging operations to be
carried out in closed systems, i.e. using glove box and
doverpac containment technology.
Handling of 5-fluoro-2-oxindole should only be carried out
using nitrile gloves to standard EN 374, safety glasses to
standard EN 166, NIOSH approved fullface mask respirator
with a silicon rubber mask to comply with EN 136 and a visor
to standard EN 166. Filter complies with standards EN
141.2000/EN 12941/EN12942.
In the event of spillage (open handling) - evacuate area.
Clean up personnel should wear NIOSH approved fullface mask
respirator with filter, chemical resistant gloves to
standard EN 374 and rubber boots. Sweep up spill ensuring
to avoid dust generation, and place in clean, dry
containers for disposal (incineration). Once material spill
has been collected - wash spill site with water, taking care
to keep out of sewers & drains.
(PPE: respiratory, skin and eye protection to prevent
overexposure)
Storage: Store in tightly closed containers, in a cool dry, well
ventilated area.
The product is incompatible with strong oxidizing materials.
Keep away from oxidizing substances.
Packaging of the substance and or preparation: The test substance should be packaged in a 500mm x 850mm
double polyethylene liner (e.g., a bag within
a bag) inside a sealed (e.g., lever lock lid) 31 L UN fiber
drum. The material can be shipped under ambient conditions.
Transport information
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Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
Stability and reactivity
Danger other than fire: Toxic
Chemical reaction with water: Will not react with water.
Dust explosion: Dust explosion is possible.
Dust explosion determined by test: N
Disposal considerations
Industry - Possibility of recovery/recycling: Not applicable.
Industry - Possibility of neutralisation: Not applicable.
Industry - Possibility of destruction: controlled discharge: Not applicable.
Industry - Possibility of destruction - incineration: All waste to be sent off site for incineration.
Industry - Possibility of destruction - water purification: Not applicable.
Industry - Possibility of destruction - other: Not applicable.
Public at large - Possibility of recovery/recycling: Not applicable.
Public at large - Possibility of neutralisation: Not applicable.
Public at large - Possibility of destruction: controlled discharge: Not applicable.
Public at large - Possibility of destruction - incineration: Not applicable.
Public at large - Possibility of destruction - water purification: Not applicable.
Public at large - Possibility of destruction - others: Not applicable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.