Registration Dossier
Registration Dossier
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EC number: 431-060-1 | CAS number: 153719-38-1
Endpoint summary
Administrative data
Description of key information
Three reliable acute toxicity studies are available. An acute oral toxicity study according OECD 401 with an LD50 between 1000 and 2000 mg/kg bw , an acute inhalation toxicity study with dusts according OECD 403 establishing a LC50>6920mg/m³and an acute dermal toxicity study according OECD 402 showing no signs of acute toxicity after single dose, dermal administration in male and female rats (LD50>2000 mg/kg bw).
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 1 500 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 6 920 mg/m³ air
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Additional information
The substance is not acutely toxic to mammals, following dermal or inhalation exposure.
Following oral exposure, the LD50 of CA 2343 A is between 1000 and 2000 mg/kg bw. With linear interpolation the LD50 (females) and LD50 (males) was determined to be 1500 mg/kg bw and 1830 mg/kg bw, respectively. Therefore, the test substance is classified for acute oral toxicity as Acute Tox. 4.
Justification for classification or non-classification
According Regulation (EC) No 1272/2008 LD50-doses of less than 2000 mg/kg indicate acute toxicity. As the oral LD50 of CA 2343 A is < 2000 mg/kg bw the substance is classified for acute oral toxicity category 4.
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