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EC number: 233-046-7 | CAS number: 10025-87-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Aquatic toxicity data on three trophic levels are available either on phosporyl trichloride (POCl3), phosphorus trichloride (PCl3) or phosphorus pentachloride PCl5 (OECD SIDS, SIAM 19, Oct 2004). The data on PCl3 and PCl5 can be used to assess the toxicity of POCl3 since phosphorus trichloride hydrolyzes to hydrochloric acid and phosphonic acid. Phosphonic acid and phosphorus acid are tautomeric molecules. Phosphorus acid is slowly oxidized by oxygen (air) to phosphoric acid (Merck 2001). And phosphorus pentachloride reacts vigorously with water and hydrolyzes to hydrochloric acid and phosphoric acid in two stages (Greenwood and Earnshaw, 1988). Both substance yield to the same hydrolysis products like POCl3.
Short-term toxicity to fish (OECD SIDS, SIAM 19, Oct 2004)
PCl3 was tested in a static limit test according to the method proposal of the German Environmental Protection Ageny “Lethal effects on Brachydanio rerio” using zebrafish (Danio rerio, Bayer AG 1991). The pH was adjusted. No effects could be observed within 96 h and the LC0 was determined to be ≥ 1000 mg/L. This value equals a LC0 of ≥ 597 mg/l of (neutralized) phosphonic acid as the hydrolysis product.
Additional results on toxicity to fish are available using PCl3 and PCl5. However, all studies were conducted without adjustment of the pH. Therefore, the results should not be used in hazard assessment since the effects were solely caused by low pH.
Short-term toxicity to aquatic invertebrates (OECD SIDS, SIAM 19, Oct 2004)
POCl3 and PCl3 were tested in an acute toxicity test according to the European guideline 92/69/EEC, method C.2 (equivalent to OECD TG 202) using Daphnia magna. In the non-buffered test solution the pH decreased from pH 7.9 in the controls to pH 6.7 at 25 mg/l, pH 3.7 at 50 mg/l, and pH 3.0 at 100 mg/l, each at the start of the incubation. For a test period of 24 h, an EC0 of 25 mg/l, an EC50 of 35.4 mg/l, and an EC100 of 50 mg/l were obtained. The same effect concentrations were measured after a test period of 48 hours. In the buffered test solution (pH 7.9) no effect was observed at the highest tested concentration of POCl3 (nominal 100 mg/l), suggesting that the effects in the non-buffered solutions were solely due to the pH decrease (Bayer AG, 2003b). The same results were obtained with PCl3 (Bayer AG, 2003c).
Toxicity to aquatic algae (OECD SIDS, SIAM 19, Oct 2004)
POCl3 and PCl3 were tested in an acute toxicity test according to the European guideline 92/69/EEC, method C.3 (equivalent to OECD TG 201) using Desmodesmus subspicatus. Both substances were tested in buffered and non-buffered test solutions. In the non-buffered solution, the pH depended on the nominal POCl3 concentration was pH 8.2 in the controls and pH 2.9 at 100 mg (nominal concentration at the start of the incubation period). In the non-buffered solution, a 72 h-ErC50 of 32 mg/l and a 72 h-EbC50 of 28 mg/l was determined. The 72h-NOEC was 12.5 mg/l for both growth rate and biomass. In buffered solution no effect was observed at the highest POCl3 concentration tested (nominal 100 mg/l). Thus, it can be concluded that the effects found in this study are caused by pH effects (Bayer AG, 2003d). Similar results were obtained with PCl3 (Bayer AG, 2003e).
Toxicity to microorganisms (OECD SIDS, SIAM 19, Oct 2004)
An acute toxicity test was conducted according to ISO 8192 (Test for the Inhibition of Oxygen Consumption by Activated Sludge) using activated sludge. After 3 h incubation an EC50 of 9450 mg/l and an EC0 of 3520 mg/l were determined (Bayer AG, 1991).
In overall conclusion, phosphoryl trichloride and its hydrolysis products are with high probability acutely not harmful to aquatic organisms and the inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
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