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EC number: 687-349-8 | CAS number: 173194-95-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- May 28th to July 4th 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: done under OECD method and GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- (6-hydroxynaphthalen-2-yl)boronic acid
- EC Number:
- 687-349-8
- Cas Number:
- 173194-95-1
- Molecular formula:
- C10H9BO3
- IUPAC Name:
- (6-hydroxynaphthalen-2-yl)boronic acid
- Test material form:
- other: Solid
- Details on test material:
- Off-white solid
Stored at normal temperature
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- The fresh activated sludge used in the test was collected from Wuzhong district urban area sewage treatment plant . The address of the plant is No. I , Baodai East Road, Suzhou city. The batch No. of inoculum was AS-20140529-0 I.
The activated sludge was washed with test medium after removing the suspended solids and coarse particles on the day of collection, the activated sludge was centrifuged at 1 100 g for 5 minutes, and the supernatant was discarded. Repeated the process for 3 times.
The dry weight content of the activated sludge was determined in triplicates after pre-treatment, and the average value was 9.91%. - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Test temperature: 22±2 'C . Monitor the temperature daily, and its range was 2 1 .0-23.7'C.
- pH: 6.79-7.39
- Aeration of dilution water: 6.04-8.68 mg/L
- Continuous darkness: yes
TEST SYSTEM
- Number of culture flasks/concentration: 5 liter glass bottles, covered with aluminium foil to keep dark. 3 liters per container which will be aerated and stirred-According to the test guideline 3028, the concentration of prepared activated sludge based on dry weight must be in the range 0.2-1 .0 g/L, and the concentration of test substance based on DOC must be between 50 mg/L and 400 mg/L. Moreover, the ratio of activated sludge and test substance must be kept in the range 2.5: I and 4: I . Therefore, 0.4 g/L of activated sludge (by dry weight) and 100 mg/L of test substance (by DOC) were used in the test, and its ratio was 4:I.
SAMPLING
Determined the DOC, pH and dissolved oxygen by Total Organic Carbon Analyzer on 3h ± 30rni n , day 0, l , 5, 8, 1 1, 14, 18, 22, 27 and 28 after the test performed. 50 mL of sample will be taken immediately prior to each sampling, replace losses due to evaporation by the concave surface marking.
CONTROL AND BLANK SYSTEM
- Inoculum blank: none
- Procedure control: diethylene glycol
- Test suspension: test substance (boronic acid)
Reference substance
- Reference substance:
- diethylene glycol
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 16.67
- Sampling time:
- 28 d
- Details on results:
- Points of degradation plot (test substance): 11.92 % degradation on 14 d and 16.67 % degradation on 28 d.
BOD5 / COD results
- Results with reference substance:
- Points of degradation plot (reference substance): 98.01 % degradation on 14 d.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- inherently biodegradable, fulfilling specific criteria
- Conclusions:
- The test material attained 16.67% degradation after 28 days and therefore can be considered to be inherently biodegradable under the strict terms and conditions of OECD Guideline No 302B.
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