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Diss Factsheets
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EC number: 940-422-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Glucamide 818 read across justification 'Aquatic ecotoxicity'
For read across the following C chain homologeuous Glucamides are used, being already registered under REACH:
Public name | REACH name | EC No. | Carbon chain | |||||
Glucamide 810 | 1-deoxy-1-[methyl(C8-10-(even)-alkanoyl)amino]-D-glucitol, REACH Registration No. 01-2120028964-50-0000 |
940-284-2 | C8-10 | |||||
Glucamide 1214 | A 3:1 mixture of: 1-deoxy-1-[methyl-(1-oxododecyl)amino]-D-glucitol; 1-deoxy-1-[methyl-(1-oxotetradecyl)amino]-D-glucitol, REACH Registration No. 01-0000015674-66-0001 |
407-290-1 | C12-14 | |||||
Glucamide 1618 | A mixture of: 1-deoxy-1-[methyl-(1-oxohexadecyl)amino]-D-glucitol; 1-deoxy-1-[methyl-(1-oxooctadecyl)amino]-D-glucitol, REACH Registration No. 01-0000015858-56-0000 |
411-130-6 | C16-18 |
Based on the typical composition of Glucamide 818 65.7% a.i. is related to C12 & C14 homologues (Glucamide 1214) and 13.8% a.i. to C8 & 10 (Glucamide 810). C16 to C18 & C18-1 account for 17.3% a.i. only. This means that the aquatic ecotoxicity values for Glucamide 818 should be higher than the ones from Glucamide 1214 but lower than the values from Glucamide 810.
For read across the lower aquatic ecotoxicity values will be taken, means the values from Glucamide 1214 (worst case).
In the table below an overview on the acute & chronic aquatic ecotoxicity of the the registration substance Glucamide 818 is given together with the data from Glucamide 1214. Comparing the data from Glucamide 818 and Glucamide 1214 shows that GA 1214 can be used for read across for the missung acute and chronic fish data of Glucamide 818 as the other acute and chronic data of both substance are in the same order of magnitude. Read across for the fish data avoids verterbrate testing and contributes to animal welfare.
Table Summary of the available acute & chronic aquatic ecotoxicity data of Glucamide 818 and Glucamide 1214
Type | Species | Guideline | Endpoint | GA 818 (a.i.) | GA 1214 (a.i.) | |
Acute fish | Danio rerio | OECD 203 | LC50 (96h) | 7.5 mg/L (RA GA1214) |
7.5 mg/L | |
Acute daphnia | Daphnia magna | OECD 202 | EC50 (48h) | 5.9 mg/L | 18 mg/L | |
Algae | S. capricornutum | OECD 201 | ErC50 (96h) | 49 mg/L | 30 mg/L | |
Microorganisms | Sewage sludge | OECD 209 | NOEC (3h) respiration inhibition | 8.1 mg/L | 8.9 mg/L | |
Chronic fish | Danio rerio | OECD 210 | NOEC (35d) mortality | 4.8 mg/L (RA GA1214) |
4.8 mg/L | |
Chronic daphnia | Daphnia magna | OECD 211 | NOEC (21d) mortality | 3.2 mg/L | 4.3 mg/L | |
Algae | S. capricornutum | OECD 201 | ErC10 (96h) | 7.2 mg/L | 6.4 mg/L |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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