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EC number: 231-104-6 | CAS number: 7439-95-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Magnesium (as chloride or sulphate) has of relatively low acute toxicity (LD50, oral, rat: ≥ 2000 mg/kg bw day);
Magnesium (as chloride) has of relatively low acute toxicity ( LD50, dermal, rat: >2000 mg/kg bw day);
Magnesium (as hydroxide) has of relatively low acute toxicity (LC50, inhalation, rat: 2100 mg/m3);
It is concluded that the substance Magnesium does not meet the criteria to be classified for human health hazards for Acute dose toxicity.
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Well documented study which meets basic scientific principles
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
- Deviations:
- no
- GLP compliance:
- not specified
- Test type:
- acute toxic class method
- Limit test:
- yes
- Species:
- rat
- Strain:
- Wistar
- Sex:
- female
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS (The animals were derived from a controlled full barrier maintained breeding system (SPF). According to Art. 9.2, No.7 of the German Act of Animal Welfare the animals were bred for experimental purposes.)
- Source: Charles River, 97633 Sulzfeld, Germany
- Age at study initiation: 8 - 12 weeks old
- Weight at study initiation: Animals no. 1 - 3, step 1: 151 - 158 g; Animals no. 4 - 6, step 2: 161 -170 g
- Fasting period before study: Prior to administration food was withhel from the test animals for 16 to 19 hours (access to water was permitted). Food was provided again approximately 3 -4 hours post dosing.
- Housing: full-barrier in an air-conditioned room; The animals were kept in groups in IVC cages, type III H, polysulphone cages on Altromin saw fibre bedding (lot no. 06.06.09)
- Diet: Free access to Altromin 1324 maintenance diet for rats and mice (lot no. 1452)
- Water: Free access to tap water, sulphur acidified to a pH value of approx. 2.8 (drinking water, multicipal residue control, microbiological control at regular intervals.)
- Acclimation period: 6 days
ENVIRONMENTAL CONDITIONS
- Temperature: 22 +/- 3 °C
- Relative humidity: 55 +/- 10%
- Air changes: 10x / hour
- Photoperiod (hrs dark / hrs light): 12/12
No further information on the test animals was stated. - Route of administration:
- oral: gavage
- Vehicle:
- water
- Details on oral exposure:
- VEHICLE
Aqua ad injection (sterile water, B. Braun Melsungen, lot no. 7494A191, expiry date: 11.2010)
- Justification for choice of vehicle: This vehicle was chosen due to its non-toxic characteristics.
DOSAGE PREPARATION: The test item was weighed out into a tared vial on a precision balance. A solution with the vehicle (Aqua ad injectionem (sterile water)) was prepared.
For all animals of the first and second step, 2 g of the test item were dissolved in the vehicle to gain a final volume of 5 mL and to achieve a dose of 2000 mg/kg body weight at a dose volume of 5 mL/kg body weight. The test item was administered at a dose volume of 5 mL/kg body weight.
The dose formulations were made shortly before each dosing occasion.
No further information on the oral exposure was stated. - Doses:
- 2000 mg/kg body weight
- No. of animals per sex per dose:
- 3 female rats per step (Total: 6 female rats)
- Control animals:
- no
- Details on study design:
- - Duration of observation period following administration: All animals were observed for 14 days after dosing for general clinical signs morbidity and mortality.
- Frequency of observations and weighing: Prior to the administration a detailed clinical observation was made of all animals. Following the period of fasting the animals were weighed and the test item was administered. The animals were also weighed on days 8 and 15 after administration. A careful clinical examination was maade several times on the day of dosing (at least once during the first 30 minutes and with special attention given during the first 4 hoours post-dose). Thereafter, the animals were observed for clinical signs once daily until the end of the observation period. All abnormalities were recorded.
Cageside observations included changes in the skin and fur, eyes and mucous membranes. Also, respiratory, circulatory, autonomic and central nervous systems and somatomotor activity and behaviour pattern were examined. Particular attention was directed to observations of tremor, convulsions, salivation, diarrhoea, lethargy, sleep and coma.
- Necropsy of survivors performed: Yes
At the end of the observation period the animals were sacrificed with an overdosage of pentobarbital injected intraperitoneally (Narcoren®, manufacturer: Merial; lot no.: 193089; expiry date: 08.2012) at a dosage of approx. 8 mL/kg bw.
All animals were subjected to gross necropsy. All gross pathological changes were recorded.
No further information on the study design was stated. - Statistics:
- No data
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: LD50 cut off value: 5000 mg/kg body weight
- Mortality:
- No mortality was observed.
- Clinical signs:
- No signs of toxicity were observed in any of the animals.
- Body weight:
- The weight gain of the animals was within the expected range.
- Gross pathology:
- No special gross pathological changes were recorded for any animal.
- Other findings:
- No data
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Under the conditions of the present study, a single oral application of the test item magnesium chloride hexahydrate to rats at a dose of 2000 mg/kg body weight was associated with no signs of toxicity or mortality.
The median lethal dose of magnesium chloride hexahydrate after a single oral administration to female rats, observed over a period of 14 days is :
LD50 cut off (rat): 5000 mg/kg body weight. - Executive summary:
Two groups, each of three female WISTAR Crl: WI(Han) rats, were treated with Magnesium Chloride hexahydrate by oral gavage administration at a dosage of 2000 mg/kg body weight . The animals were observed on delivery, on inclusion in the study and before administration for mortality/morbidity and other clinical signs. All animals were examined for clinical signs several times on the day of dosing and once daily until the end of the observation period. Their body weights were recorded on day 1 (prior to the administration) and on days 8 and 15. All animals were necropsied and examined macroscopically.
Throughout the 14-day observation period, all animals survived until the end of the study without showing any signs of toxicity. In conclusion, the median lethal dose of Magnesium chloride hexahydrate after a single oral administration to female rats, observed over a period of 14 days is 5000 mg/kg body weight (LD50 cut off).
Reference
Absolute Body Weights in g and Body Weight Gain in %
Animal no. / sex |
g |
g |
g |
% |
Step 1 |
||||
1 / female |
158 |
182 |
192 |
+22 |
2 / female |
155 |
176 |
187 |
+21 |
3 / female |
151 |
165 |
171 |
+13 |
Step 2 |
||||
4 / female |
170 |
203 |
215 |
+26 |
5 / female |
161 |
182 |
199 |
+24 |
6 / female |
162 |
194 |
204 |
+26 |
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Acute toxicity: via inhalation route
Link to relevant study records
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Well documented study which meets basic scientific principles
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 403 (Acute Inhalation Toxicity)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.2 (Acute Toxicity (Inhalation))
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 870.1300 (Acute inhalation toxicity)
- Deviations:
- no
- GLP compliance:
- not specified
- Test type:
- acute toxic class method
- Limit test:
- yes
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- Species
Rat: Crl:WI(Han) (outbred, SPF-Quality)
Recognised by international guidelines as the recommended test system (e.g. OECD, EC).
Source: Charles River Deutschland, Sulzfeld, Germany.
Number of animals
5 males and 5 females (females were nulliparous and non-pregnant) per exposure level.
Age and body weight
Young adult animals were selected (approximately \ weeks old).
Animals used within the study were of approximately the same age and body weight variation did not exceed +/- 20% of the sex mean.
Identification
Earmark
Health inspection
A health inspection was performed prior to commencement of treatment, to ensure that the animals were in a good state of health. - Route of administration:
- inhalation: aerosol
- Type of inhalation exposure:
- whole body
- Vehicle:
- air
- Details on inhalation exposure:
- Test atmosphere generation
Administering the test substance to a stream of dry pressurized air using a combination of a spiral feeder and air mover generated an aerosol. The aerosol was passed through a cyclone, allowing larger particles to settle, before it entered the exposure chamber (Appendix 1, Figure 1). The mean total airflow was 47 L/min. From the exposure chamber the test atmosphere was passed through a filter before it was released to the exhaust of the fume hood.
Nominal concentration
The nominal concentration was calculated by dividing the amount of test substance used by the volume of pressurized air (average air flow times exposure time) entering the exposure chamber used for exposure of the animals.
Actual concentration
The actual concentration was determined twelve times during the exposure period. Samples were drawn from the test atmosphere through a tube mounted in one of the free animal ports of the middle section of the exposure chamber. Samples were drawn through a glass fiber filter (type APFC04700, Millipore, Billerica, MA, USA). The collected amount of the test substance in the air sample was measured gravimetrically. Sample volumes were measured by means of a dry gas meter (type G 1.6, Actaris Meterfabriek B.V., Dordrecht, The Netherlands).
Subsequently the mean concentration with the standard deviation was calculated.
The particle size distribution was characterized twice during the exposure period. The samples were drawn (2 L/min) from the test atmosphere through a tube mounted in one of the free animal ports of the middle section of the exposure chamber (Appendix 1, Figures 1 and 2). The samples were collected with an 8 stage Marple personal cascade impactor containing fiber glass filters (SKC 225-713, fiber glass, SKC Omega Specialty Division, Chelmsford, MA, USA) and a fiber glass back-up filter (SEC-290-GFS, Westech, Upper Stondon, Bedfordshire, England). Amounts of test substance collected were measured gravimetrically. Subsequently the Mass Median Aerodynamic Diameter (MMAD) and the Geometric Standard Deviation (GSD) were determined. - Analytical verification of test atmosphere concentrations:
- yes
- Remarks:
- The collected amount of the test substance in the air sample was measured gravimetrically. Sample volumes were measured by means of a dry gas meter (type G 1.6, Actaris Meterfabriek B.V., Dordrecht, The Netherlands).
- Duration of exposure:
- 4 h
- Concentrations:
- The mean actual concentration was 2.1 ± 0.47 mg/L. The nominal concentration was 21.7 mg/L resulting in a generation efficiency (ratio of actual and nominal concentration) of 10%. The concentration measurements distributed over time showed that the substance was sufficiently stable
- No. of animals per sex per dose:
- 5 males and 5 females
- Control animals:
- no
- Details on study design:
- - Duration of observation period following administration: 15 days
- Frequency of observations and weighing: Days 1 (pre-administration), 2, 4, 8 and 15.
- Necropsy of survivors performed: yes
- Other examinations performed: clinical signs, body weight,organ weights, histopathology, other: On Day 1, one and three hours after exposure and once daily thereafter until Day 15. - Statistics:
- No statistical analysis was performed.
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- > 2.1 mg/L air
- Based on:
- test mat.
- Exp. duration:
- 4 h
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- > 2 100 mg/m³ air
- Based on:
- test mat.
- Exp. duration:
- 4 h
- Remarks on result:
- other: To convert mg/l into mg/m³ 1 mg/m³ = mg/l x 1000 (2.1 x 1000=2100 mg/m³)
- Mortality:
- No mortality occurred.
- Clinical signs:
- other: No clinical signs were noted during exposure. After exposure, ptosis and/or piloerection were noted in two males and one female on Day 1 only.
- Body weight:
- Overall body weight gain in males and females was within the range expected for rats of this strain and age used in this type of study.
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: OECD GHS
- Conclusions:
- The inhalatory LC50, 4h value of Magnesium hydroxide in Wistar rats was established to exceed 2.1 mg/L.
- Executive summary:
Groups of 5 male and female Wistar rats were treated with Magnesium hydroxide as aerosol during 4 hours. No mortality or other relevant adverse effects were observed. An inhalatory LC50 (4h)value for magnesium hydroxide exceeding 2.1 mg/L was determined, being this value the maximum feasible concentration that could be tested.
Reference
To convert mg/l into mg/m³
1m³=1000L
1 mg/m³=mg/l x 1000, 2.1mg/l x1000=2100 mg/m³
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LC50
- Value:
- 2 100 mg/m³
Acute toxicity: via dermal route
Link to relevant study records
- Endpoint:
- acute toxicity: dermal
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- Deviations:
- yes
- Remarks:
- One female animal was slightly below 200 g but this animal was only of 2 g below the accepted range, it was included in the study.
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- Species/strain: Healthy rats, WISTAR Crl: WI(Han) (Full-Barrier)
Source: Charles River, 97633 Sulzfeld, Germany
The female animals were nulliparous and non-pregnant.
Body weight at the beginning of the study: females: 198 - 222 g, males: 241 – 262 g
Age at the beginning of the study: females: 18 - 19 weeks old, males: 8 -9 weeks old
The animals were derived from a controlled full-barrier maintained breeding system (SPF).
Housing and Feeding Conditions: full barrier in an air-conditioned room, temperature: 22 (+/-3) °C, relative humidity: 55 (+/- 10)%, artificial light, sequence being 12 hours light, 12 hours dark, air change: 10 x / hour, free access to Altromin 1324 maintenance diet for rats and mice, free access to tap water, sulphur acidified to a pH value of approx. 2.8 (drinking water, municipal residue control, microbiological control at regular
intervals), the animals were kept individually in IVC cages, type III H, polysulphone cages on Altromin saw fibre bedding, adequate acclimatisation period. - Type of coverage:
- semiocclusive
- Vehicle:
- water
- Remarks:
- Aqua ad injectionem
- Details on dermal exposure:
- Approximately 24 hours before the test, the fur was removed from the dorsal area of the trunk by using an electric clipper. Care was taken to avoid abrading the skin, and only animals with healthy intact skin were used.
No less than 10 % of the body surface was cleared for the application.
The test item was applied at a single dose, uniformly over an area which was approx. 10 % of the total body surface. - Duration of exposure:
- The test item was held in contact with the skin throughout a 24-hour period. At the end of the exposure period residual test item was not removed.
- Doses:
- 2000 mg/kg body weight
- No. of animals per sex per dose:
- 5 males and 5 females
- Control animals:
- no
- Details on study design:
- Prior to the application, a detailed clinical observation was made of all animals.
All animals were observed for 14 days after dosing.
The animals were weighed on day 1 (prior to the application) and on days 8 and 15.
A careful clinical examination was made several times on the day of dosing (at least once during the first 30 minutes and with special attention given during the first 4 hours post-dose). As soon as symptoms were noticed they were recorded. Thereafter, the animals were observed for clinical signs once daily until the end of the observation period. All abnormalities were recorded.
Cageside observations included changes in the skin and fur, eyes and mucous membranes. Also respiratory, circulatory, autonomic and central nervous systems and somatomotor activity and behaviour pattern were examined. Attention was directed to observations of tremors, convulsions, salivation, diarrhea, lethargy, sleep and coma.
At the end of the observation period, the animals were sacrificed by an overdosage of pentobarbital injected intraperitoneally. All animals were subjected to gross necropsy. All gross pathological changes were recorded. - Statistics:
- Signs of erythema and oedema were assessed using the scoring system laid down in OECD Guideline 404.
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- No
- Clinical signs:
- The test item showed slight signs of dermal irritation (slight scratches) after a single dose application for one female (n°14) on day 3 and 4.
The clinical signs observed were seen only on the day of application and may partly be due to the stress induced by the application procedure. These signs are:
- Red nasal discharge for one female (n°15) at 2, 3 and 4 hours and for 3 males (n°21, 23, 24) at 1, 2, 3 and 4 hours.
- Diarrhea for one male (n°21) immediatly after the application, 30 mn and 1 hour. - Body weight:
- The body weight development of all male and female animals was within the expected range.
- Gross pathology:
- At necropsy, female no. 14 showed changes of the tissue on the large intestine, which was filled with liquid. As this finding was seen in only one animal and was not associated with any specific clinical signs, this finding was most probably not test item related.
- Other findings:
- No
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Under the conditions of this study, the dermal LD50 was determined to be > 2000 mg Magnesium chloride hexahydrate/kg body weight.
- Executive summary:
Under the conditions of this study, single dermal application of the test item Magnesium chloride hexahydrate to rats at a dose of 2000 mg/kg body weight was associated with no mortality.
The dermal LD50 was determined to be > 2000 mg Magnesium chloride hexahydrate/kg body weight.
Reference
Absolute Body Weights in g and Body Weight Gain in %
Animal No. / Sex |
Day 1 |
Day 8 |
Day 15 |
% Day 1 - 15 |
11 female |
222 |
219 |
219 |
-1 |
12 female |
201 |
208 |
213 |
6 |
13 female |
218 |
216 |
215 |
-1 |
14 female |
214 |
217 |
215 |
0.5 |
15 female |
198 |
195 |
200 |
1 |
21 male |
262 |
288 |
315 |
20 |
22 male |
256 |
275 |
303 |
18 |
23 male |
241 |
268 |
291 |
21 |
24 male |
244 |
264 |
286 |
17 |
25 male |
247 |
273 |
302 |
22 |
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Additional information
Acute toxicity: oral
The acute oral toxicity study in Sprague-Dawley rats following acute toxic class method [OECD TG 423] in compliance with Good Laboratory Practice (GLP). Magnesium sulfate was orally administeredatdose levels of 300 (1stand 2ndsteps) and 2,000 (3rdand 4thsteps) mg/kg to 3 female rats (9 to 10 weeks old) per study step.Based on these results, the acute oral LD50 value was ≥ 2,000 mg/kg bw for female rats
A single oral application of the test item magnesium chloride hexahydrate to rats at a dose of 2000 mg/kg body weight was associated with no signs of toxicity or mortality.The median lethal dose of magnesium chloride hexahydrate after a single oral administration to female rats, observed over a period of 14 days is :LD50 cut off (rat): 5000 mg/kg body weight.
Acute Dermal Toxicity:
Single dermal application of the test item Magnesium chloride hexahydrate to rats at a dose of 2000 mg/kg body weight was associated with no mortality.
The dermal LD50 was determined to be > 2000 mg /kg body weight.
Acute Inhalation toxicity:
The inhalatory LC50, 4h value of Magnesium hydroxide in Wistar rats was established to exceed 2100mg/m3
Justification for classification or non-classification
Based on the hazard assessment of Magnesium (CAS No. 7439 -95 -4), in section 2.1 and 2.2. in IUCLID 5.4., available data for the substance and following the “Guidance on Information Requirement and Chemical Safety Assessment R.8. Characterisation of dose [concentration]- response for human health”, according to the EU’s list of dangerous substances (OJEC No L200/130.7.99) and according to the criteria described in Directive 67/548 and in the CLP Regulation:
Directive 67/548 |
Very Toxic (T+) R28: Very toxic if swallowed R27: Very toxic in contact with skin R26: Very toxic by inhalation R39/26 R39/27 R39/28: Dangerous of very serious irreversible effects Toxic (T): R25: Toxic if swallowed R24: Toxic in contact with skin R23: Toxic by inhalation R39/23 R39/24 R39/25: Danger of very serious irreversible effects Harmful (Xn): R22: Harmful if swallowed R21: Harmful in contact with skin R20: Harmful by inhalation R65: Harmful may cause lung damage if swallowed R21/22 Harmful; Harmful in contact with skin and if swallowed. R68/20 R68/21 R68/22: Possible risk of irreversible effects Other toxicological properties R67: Vapours may cause drowsiness and dizziness |
CLP |
H300 Acute Tox. 2 Fatal if swallowed H310 Acute Tox. 1 Fatal in contact with skin H330 Acute Tox. 2 Fatal if inhaled H370 STOT SE 1 H301 Acute Tox. 3 Toxic if swallowed H311 Acute Tox. 3 Toxic in contact with skin H331 Acute Tox. 3 Toxic if inhaled H370 STOT SE 1 H302 Acute Tox. 4 Harmful if swallowed H312 Acute Tox. 4 Harmful in contact with skin H332 Acute Tox. 4 Harmful if inhaled H304 Asp. Tox. 1 H371 STOT SE 2 (May cause damage to organs (or state all organsaffected if known) (state route of exposure if it is conclusively proventhat no other routes of exposure cause the hazard) Other toxicological properties H336 STOT SE 3 May cause drowsiness or dizziness
|
It is concluded that the substance Magnesium (CAS No. 7439 -95-4), does meet the criteria to be classified for human health hazards for acute oral, inhalation and dermal effects.
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