Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 938-868-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Cu(II)-IDHA_OECD201_Pseudokirchneriella subcapitata: ErC50 (72h) > 250 mg/L; NOEC (72h) = 1 mg/L
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 250 mg/L
- EC10 or NOEC for freshwater algae:
- 1 mg/L
Additional information
The acute toxicity of Cu(II)IDHA towards the green algae Pseudokirchneriella subcapitata was investigated in a 72 hours static toxicity laboratory study according to OECD 201 and in compliance with GLP (Rzodeczko, 2011). The initial density of algae was 10 000 cells/mL. The following concentrations of the test item Cu(II) IDHA were applied: 1.0; 2.6; 6.4; 16; 40; 100 and 250 mg/L. The test item Cu(II) IDHA contains aspartic acid (N-1,2 dicarboxyethyl) complexed with copper. The effect of algal growth inhibition is related with test item and increases with test concentration. In highest test concentration 250 mg/L the observed inhibition of algal growth may be overlapped with indirect effect related to blue colour of the solution. In test concentrations 6.4; 16; 40 and 100 mg/L few algae cells of twice the size of algal cells in the control were observed with microscope. In the highest test concentration 250 mg/L different types of algae cells were observed, i.e. some rod-shaped cells, some S-shaped cells, few cells bigger of twice the size of normal cells, few cells without changes of normal size and shape. No differences in size or shape of algal cells in lowest test concentrations 1.0 and 2.6 mg/L were observed as compared to the algae cells in the control. The ECx values were determined based on nominal concentrations of Cu(II) IDHA.
The determined ErC50 (72h) is higher than 250 mg/L (the highest test concentration) whereas EyC50 (72h) amounts to 54.57 mg/L. The ErC10 (72h) value is 18.41 mg/L. The LOEC (Lowest Observed Effect Concentration) and NOEC (No Observed Effect Concentration) values are 2.6 mg/L and 1.0 mg/L, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.