α,α,α',α'-tetramethyl-m-xylene-α,α'-diol

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

March 2011

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Well conducted study according to EU draft and ISO guidelines, under Internal Management System and certificate of analysis included in the report.

Qualifier:

according to guideline

Guideline:

other: ISO2591-1, Test sieving – Part 1: Methods using test sieves of woven wire cloth and perforated metal plate, December 1988

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: ISO 3310-1, Test sieves – Technical requirements and testing – Part 1: Test sieves of metal wire cloth, July 1990

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: Intern Akzo Nobel SMA 721.02, Determination of the particle size distribution of powders and granular products

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: Intern AkzoNobel SMA743.02, Distribution of powders and granulated products in representative portions, August 1993

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: DRAFT EUR 20268 EN Guidance document on the determination of particle size distribution, fiber length and diameter distribution of chemical substances, 2002

Deviations:

no

GLP compliance:

no

Remarks:

Internal Management System

Type of method:

sieving

Type of distribution:

other: passing 100 µm sieve

Percentile:

D50

Mean:

< 100 µm

Remarks on result:

other: No particles pass the sieve. (migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.)

Light microcopic examination

The picture in the report shows that a small amount of particles < 100 µm is present. The shape of these fines is non-fibrous. See attachment.

Sieving

 

Fraction	Pot 2		Pot 3
	[g]	[%]	[g]	[%]
< 100µm	0.00	0.0	0.00	0.0
> 100µm	100.49	100.0	105.50	100.0

 

It is shown that no particles pass the 100 µm sieve. The presence of water makes the product more sticky and the (fine) particles agglomerate. Consequently no PSD(Particle Size Distribution)  has to be determined.

Conclusions:

Light microscopic examination revealed that the α,α,α',α'-tetramethyl-m-xylene-α,α-diol contains a small amount of particles < 100 µm. The shape of these fines is non-fibrous.
No particles pass the 100 µm sieve. The presence of water makes the product more sticky and the (fine) particles agglomerate. As a result α,α,α',α'-tetramethyl-m-xylene-α,α-diol is not dusty.
There is no inhalation risk related to α,α,α',α'-tetramethyl-m-xylene-α,α-diol.

Executive summary:

The granulometry of α,α,α',α'-tetramethyl-m-xylene-α,α-diol was determined in accordance with European Chemicals Agency (ECHA), Guidance on information requirements and chemical safety assessment, Chapter R.7a, Endpoint specific guidance, May 2008.

Description of key information

There is no inhalation risk related to α,α,α',α'-tetramethyl-m-xylene-α,α-diol. Light microscopic examination revealed that the α,α,α',α'-tetramethyl-m-xylene-α,α-diol contains a small amount of particles < 100 µm. The shape of these fines is non-fibrous.

No particles pass the 100 µm sieve. The presence of water makes the product more sticky and the (fine) particles agglomerate. As a result α,α,α',α'-tetramethyl-m-xylene-α,α-diol is not dusty.

Additional information

The particle size distribution of the sample analysed in China of α,α,α',α'-tetramethyl-m-xylene-α,α'-diol is different than the standard sample analysed in The Netherlands by Altena.The data for granulometry are dependent on the type, production and pretreatment of the sample.