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EC number: 630-399-2 | CAS number: 130169-56-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: GLP - Guideline study with acceptable restrictions
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 996
- Report date:
- 1996
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- yes
- Remarks:
- no data on purity, no analytics
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Amines, tallow alkyl
- EC Number:
- 263-125-1
- EC Name:
- Amines, tallow alkyl
- Cas Number:
- 61790-33-8
- IUPAC Name:
- 61790-33-8
- Reference substance name:
- Amines, tallow alkyl
- IUPAC Name:
- Amines, tallow alkyl
- Details on test material:
- - Name of test material (as cited in study report): Genamin TA 100 D (Talgfettamin, dest.)
Constituent 1
Constituent 2
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: Municipal sewage treatment plant at Hildesheim
- Prereatment: The activated sludge is maintained in an aerobic condition by aeration for four hours and then homogenized with a mixer. The sludge is filtered and the filtrate is subsequently used to initiate inoculation.
- Colony forming units of the inoculum: ca. 18x10^4 (CFU/mL)
- Colony forming units in the test vessels: ca. 18x10^2 (CFU/mL)
The guideline recommends the range of colony forming units between 10^6 and 10^8 (colony forming units/mL). Chosen was a bacterial density, which in experience quickly adapted considering the biodegradation of the ready biodegradable functional control, which is tested usually in each test series. Also the test duration of 28 days allows sufficient time for adaptation of the microorganisms to the test compounds. - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 13 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: mineral nutrient medium according to OECD 301B
- Test temperature: 23-24°C
- pH: Control: 7.5; functional control: 7.3; test substance: 7.4; toxicity control: 7.8
- pH adjusted: no
TEST SYSTEM
- Culturing apparatus: 5 L brown glass bottles filled with 3L test medium
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: aeration with CO2 free air
- Measuring equipment: Photometer, Dr. Lange CADAS 100
- Details of trap for CO2 and volatile organics if used: series of 3 gas wash bottles
SAMPLING
- Sampling frequency: day 1, 3, 6, 8, 10, 13, 16, 20, 23, 28, 29
- Sampling method: First wash bottle was removed at sampling date. CO2 was determined by titration subsequent to complete adsorption of the released CO2 in a basic solution (Backtitration of the residual Ba(OH)2 with 0,05 N HCI).
CONTROL AND BLANK SYSTEM
- Inoculum blank: 2
- Toxicity control: 1
- Reference compound: 1
Reference substance
- Reference substance:
- other: sodium acetate
Results and discussion
- Test performance:
- The relation between IC and TC content of the test substance in the mineral medium was not determined at the beginning of the test, because the test substance was not fully soluble in the test medium.
% Degradationopen allclose all
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 18
- Sampling time:
- 6 d
- Remarks on result:
- other: Replicate 1
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 50
- Sampling time:
- 16 d
- Remarks on result:
- other: Replicate 1
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 64
- Sampling time:
- 29 d
- Remarks on result:
- other: Replicate 1
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 58
- Sampling time:
- 29 d
- Remarks on result:
- other: Replicate 2
- Details on results:
- In the control group a maximum of 28.1 mg CO2/L was formed after 28 days (quality criteria : < 40 mg C02/L).
In the toxicity control the degradation came to 50 % after 13 days in a 10-day window and reached a maximum of 65 % after 28 days.
In case of the test substance the 10 %-pass level was passed after 4 days adaptation phase. In the 10-day window the test substance reached a mean degradation rate of 46 %. After 28 days a mean degradation rate of 61 % was reached.
BOD5 / COD results
- Results with reference substance:
- The adaptation phase of the functional control changes after 2 days into the degradation phase (degradation > 10 %). The course of the degradation phase is very rapid and reaches a degradation rate of 63 % already on day 8. After 13 days the C02-production corresponds to a degradation rate of 72 %. The quality criteria degradation > 60 % after 14 days was fulfilled.
Any other information on results incl. tables
The test substance must be regarded to be not readily biodegradable in the 10-day window.
Table: CO2-production and biodegradability for all determination points in the control, test substance samples and toxicity control samples.
Test day |
Control mv |
Test substance 13 mg/L |
Test substance 13 mg/L |
Toxicity control |
||||||
mg CO2 |
mg CO2 |
degr. |
mg CO2 |
degr. |
mg CO2 |
degr. |
||||
gross |
net |
% |
gross |
net |
% |
gross |
net |
% |
||
1 3 6 8 10 13 16 20 23 28 29 29 |
6.1 13.5 23.2 29.4 34.3 41.2 48.6 58.9 66.6 74.4 81.1 84.3 |
5.4 16.5 44.3 60.3 74.7 91.3 105.8 123.2 130.9 141.6 154.3 157.7 |
0 3.0 21.1 30.9 40.4 50.1 57.2 64.3 64.3 67.2 73.2 73.4 |
0 3 18 27 35 44 50 56 56 59 64 64 |
5.1 20.4 46.5 60.8 72.6 91.2 105.4 118.8 127.3 134.8 147.7 151.3 |
0 6.9 23.3 31.4 38.3 50.0 56.8 59.9 60.7 60.4 66.6 67.0 |
0 6 20 27 33 44 50 52 53 53 58 58 |
5.3 43.0 94.0 128.8 143.3 155.3 170.2 186.5 203.1 214.0 229.6 231.7 |
0 29.5 70.8 99.4 109.0 114.1 121.6 127.6 136.5 139.6 148.5 147.4 |
0 13 31 44 48 50 54 56 60 61 65 65 |
degr. = degradation
mv = mean value
Applicant's summary and conclusion
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The pass level of 10 [%] (start of the degradation phase) was reached by the test substance at the 4th day. In the 10-day-window the test substance came to a mean degradation rate of 46 [%]. After 28 days a mean degradation rate of 61 [%] was reached.
In order to check the activity of the study system sodium acetate was used as a functional control. The functional control was degraded to 72 [%] after 13 days and therefore the quality criteria of "degradation > 60 [%] after 14 days" was fulfilled.
In the toxicity control the degradation came to a rate of 50 [%] after 13 days and reached a maximum of 65 [%] after 28 days.
The criteria of the guideline that the degradation in the toxicity control should be > 25 % after 14 days was fulfilled. - Executive summary:
The ready biodegradability in the Modified Sturm Test was determined with a non adapted activated studge for the test substance Genamin TA 100 D over a period of 28 days. The study was made from January 30 to February 28, 1996 according to OECD Guidetine 301 B in the DR.U.NOACK-LABORATORIUM FÜR ANGEWANDTE BIOLOGIE.
The test substance was tested in a concentration of 13 [mg/L] in duplicates, corresponding to a carbon content of 10.4 [mgC/L].
The biological degradation of the test subsance was followed by titrimetric analyses of the quantity of CO2 which was produced by the respiration of bacteriae.
The degradation was finished on day 28, the last titration was made on day 29, after the soluble CO2 was turned out over a period of 24 [h].
The CO2 production was calculated as the percentage of total CO2 that the test substance could have theoretically produced based an carbon composition. Biodegradability is therefore expressed as a percentage ThCO2 (calculated by carbon content) and Was calculated for each titration of CO2.
In order to check the activity of the study System sodium acetate was used as functional control. The functional control was degraded to 72 [%] after 13 days and therefore the quality criteria of "degradation > 60 [%] after 14 days“ was fulfiiled.
In the toxicity control the degradation came to a rate of 50 1%) after 13 days and reached a maximum of 65 [ after 28 days.
The criteria of the guideline that the degradation in the toxicity control should be > 25 [%] after 14 days was fufilled.
The biological degradation of the test substance is shown graphically (see table below) in comparison to the readily degradabte functional control and the toxicity control.
The pass level of 10 [%] (start of the degradation phase) was reached by the test substance at the 4th day. In the 10-day window the test substance came to a mean degradation rate of 46 [%]. After 28 days a mean degradation rate of 61 [%] was reached.
Ready biodegradability of the test substance Genamin TA 100 D
in comparison to the functional control and the toxicity control
Biodegradation [%] days 6 13 20 28 test substance 19 44 54 61 toxicity control 31 50 56 65 functional control 51 72 77 84
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