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EC number: 603-894-6 | CAS number: 135108-88-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study (GLP)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- The analytical determination of the test substance concentrations was performed at the beginning and at the end of the test. The samples for analysis were taken from concentrations 70 mg.L-1 and 40 mg.L-1. All samples for analysis were delivered in transport box to analytical laboratory immediately after preparation and after end of test period (96 hours). The samples were analyzed on the day of delivery. All samples were stored at laboratory temperature.
- Vehicle:
- no
- Details on test solutions:
- Standard dilution water was prepared just before the test by admixing 2.5 mL of stored solutions A, B, C and D in 1000 mL of deionized water.
A. 117.6 g CaCl2•2H20 in 1L deionized water
B. 49.3 g MgSO4•7H2O in 1L deionized water
C. 25.9 g NaHCO3 in 1L deionized water
D. 2.3 g KCl in 1L deionized water
The dilution water should be of pH 7.8 0.2. It is saturated by oxygen by the aeration
at temperature of 20 – 24 °C. The content of sum Ca + Mg ions should have the value
of 2.5 mmol•L-1. - Test organisms (species):
- Poecilia reticulata
- Details on test organisms:
- supplier: EMPLA s.r.o., Hradec Kralove, (CZ)
length: 2.0 - 3.0 cm, healthy animals
Fish were acclimatized for 7 days in dilution water. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Hardness:
- The content of sum Ca + Mg ions should have the value of 2.5 mmol/L
- Test temperature:
- 20 - 24 °C
- pH:
- 7.8 +/- 0.2
- Dissolved oxygen:
- saturated at temparatures of 20 - 24 °C
- Salinity:
- freshwater
- Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 63 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 40 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- 70 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Results with reference substance (positive control):
- The sensitivity of the test species and correctness of test performance is periodically verified in six-month period by testing the reference substance, potassium dichromate.
The results of verification test with K2Cr2O7, carried out in period from 15.10. to 19.10. 2012, are the following:
48 hour – LC50 = 155 mg•L-1 (95% confidence limit: 126 – 184 mg•L-1)
96 hour – LC50 = 140 mg•L-1 (95% confidence limit: 90 – 190 mg•L-1) - Sublethal observations / clinical signs:
Nominal concentration
mg·L-1
70
64
58
53
48
44
40
C
Number of live fish
2 hours
10
10
10
10
10
10
10
10
Mortality %
2 hours
0
0
0
0
0
0
0
0
Number of live fish
24 hours
10
10
10
10
10
10
10
10
Mortality %
24 hours
0
0
0
0
0
0
0
0
Number of live fish
48 hours
8
9
10
9
10
9
10
10
Mortality %
48 hours
20
10
0
10
0
10
0
0
Number of live fish
72 hours
3
6
9
9
10
9
10
10
Mortality %
72 hours
70
40
10
10
0
10
0
0
Number of live fish
96 hours
0
4
8
8
9
9
10
10
Mortality %
96 hours
100
60
20
20
10
10
0
0
- Validity criteria fulfilled:
- yes
- Conclusions:
- The acute fish toxicity of Formaldehyde, polymer with benzenamine, hydrogenated was determined using OECD Test Guideline No 203.
The value of LC50 (96 h) for fish (Poecilia reticulata) was determined to be 63 mg/l. - Executive summary:
The acute fish toxicity of Formaldehyde, polymer with benzenamine, hydrogenated was determined using OECD Test Guideline No 203. Test species was Poecilia reticulata. The nominal concentrations were used for all evaluations and results because evidence is available to demonstrate that the concentration of the test substance has been satisfactorily maintained within ± 20 per cent of the nominal or measured initial concentration throughout the test.
Test validity criteria were fulfilled. The value of LC50 (96h) for fish was determined to be 63 mg/l.
Reference
Description of key information
The value of LC50 (96 h) for fish was determined to be 63 mg/l.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 63 mg/L
Additional information
The acute fish toxicity of Formaldehyde, polymer with benzenamine, hydrogenated was determined according to OECD Test Guideline No 203 with Poecilia reticulata as test species. The value of the LC50 (96 h) for fish (Poecilia reticulata) was determined to be 63 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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