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Diss Factsheets
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EC number: 212-084-8 | CAS number: 760-93-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Method in accordance with OECD Guideline, GLP.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 992
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Methacrylic acid
- EC Number:
- 201-204-4
- EC Name:
- Methacrylic acid
- Cas Number:
- 79-41-4
- Molecular formula:
- C4H6O2
- IUPAC Name:
- 2-methylprop-2-enoic acid
- Details on test material:
- purity: > 98.5 %
Batch TD 90-133
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: activated sewage sludge bacteria
- Details on inoculum:
- Aeration stage of the HRC Limited sewage treatment plant treating predominantly domestic sewage
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 3 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- other: Percent biodegradation determined by comparing oxygen depletion value with the corresponding ThOD
- Details on study design:
- Sampling at 0, 5, 15 and 28 days
20°C
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 86
- Sampling time:
- 28 d
- Remarks on result:
- other: Oxygen depletion = 4.325 mg O2/L; ThOD = 5.01 mg O2/L
- Details on results:
- Oxygen depletion in the inoculated and non-inoculated control series were within prescribed limits.
The substance passed the "time window" criterion (60% degradation within 10 days of attaining the 10% level)
BOD5 / COD results
- Results with reference substance:
- 87% degradation within 28 days
Any other information on results incl. tables
Mean oxygen depletion and percentage biodegradation values
Culture medium |
Day 5 |
Day 15 |
Day 28 |
(a) Dilution water without inoculum 02depletion (mgO2/I) |
0.175 |
0.275 |
0.250 |
(b) Dilution water with inoculum 02depletion (mgO2/I) |
0.100 |
0.300 |
0.375 |
(c) Test substance (3 mg/l) 02depletion (mgO2/I) % degradation |
3.050 61 |
3.000 60 |
4.325 86 |
(d) . Standard substance (3 mg/l) 02depletion (mgO2/I) % degradation |
3.275 65 |
3.450 69 |
4.375 87 |
t1/2: 10.3 days
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- In a valid guideline study, the substance was considered readily biodegradable (86% degradation within 28 days, 10 day window passed).
- Executive summary:
In a valid guideline study acc. OECD 301 D (Readily Biodegradability: Closed Bottlte Test) methacrylic acid attained 86 % biodegradation within 28 days. The"pass" level of 60 % was reached within 10 days of exceeding 10 % level. Therefore methacrylic acid can be termed as readily biodegradable.
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