Registration Dossier
Registration Dossier
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EC number: 236-690-7 | CAS number: 13464-97-6
Endpoint summary
Administrative data
Description of key information
No data are available for hydrazine mono-nitrate as data have been waived due to the existance of classifications. Data are available for the acute inhalation and dermal toxicity of hydrazine, indicating that it is acutely toxic via this route. Data are also available for the acute oral toxicity of hydrazine hydrate, indicating that it is of low acute toxicity via this route.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 83 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 750 mg/m³
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 91 mg/kg bw
Additional information
A dermal LD50 of 91 mg/kg bw has been identified for hydrazine in rats, and an oral LD50 of 83 mg/kg bw has been identified for hydrazine hydrate in mice. An inhalation LC50 of 750 mg/m³ has been identified in rats for hydrazine hydrate (source unsubstantiated).
Justification for classification or non-classification
Hydrazine mono-nitrate is classifiable as T; R23/24/25 Toxic; Toxic by inhalation, in contact with skin and if swallowed. under the DSD (Directive 67/548/EEC), or Acute tox 3 for oral, dermal and inhalation routes (modifiable) under CLP (Regulation 1272/2008) as per listing for 007-014-00-6 for Hydrazine Salts (group). Hydrazine Mono Nitrate is part of this group (CAS 13464-97-6).
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