6-hydroxy-1H-pyrimidin-4-one

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

06-Jul-2010 to 12-Aug-2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study conducted in compliance with OECD and EU Guidelines.

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

GLP compliance:

no

Type of method:

pycnometer method

Remarks:

gas comparison

Type:

relative density

Density:

1.655

Temp.:

20.5 °C

The calibration procedure was performed in triplicate. The individual measurements and the results are presented in Table 1.

The determination of the relative density of the test item was performed with two independent test item samples each measured in triplicate. The individual measurements are summarized in Table 2.

The tabulated values in Table 1 and Table 2 represent rounded results, which were obtained by calculation using the exact raw data.

The density of the test item was determined to be 1.655 g/cm³ (= 1.655·10³ kg/m³) at 20.5 °C using a gas comparison pycnometer.

Table 1       Results of the Calibration

Measurement	p1	p2	p3	p4	V ref	V cell
	[psi]	[psi]	[psi]	[psi]	[cm³]	[cm³]
1	17.450	5.868	17.307	6.486	7.024	13.863
2	17.502	5.883	17.263	6.471	6.981	13.787
3	17.481	5.875	17.458	6.544	6.971	13.771
Mean:					6.992	13.807

 

 

                  Calibration volume (V_cal):            2.145 cm³

 

                  Gas:                                            Helium

 

 

Table 2       Determination of the Density of the test item

 

Sample No.	Sample Weight [g]	Measure-ment	p1 (sample) [psi]	p2 (sample) [psi]	V (sample) [cm^3]	Density   [g/cm^3]
1	2.520	1	15.705	5.696	1.521	1.657
		2	15.872	5.757	1.523	1.655
		3	15.775	5.720	1.516	1.662
2	2.429	1	16.146	5.841	1.472	1.651
		2	15.705	5.681	1.470	1.652
		3	15.856	5.736	1.471	1.651
Mean:						1.655
Standard deviation ±						0.004

 

 

Calculation of the relative density

 

D₄²⁰ = 1.655 g/cm³/ 0.99997 g/cm³= 1.655

Conclusions:

The study is considered to be reliable without restrictions.

Description of key information

1.655 g/cm³, 20.5 °C, OECD 109, gas comparison pycnometer, Weissenfeld, 2010

Key value for chemical safety assessment

Relative density at 20C:

1.655

Additional information

The study was not performed under GLP, however it has been conducted in compliance with OECD and EU Guidelines.

The result is considered to be reliable and adequate for classification, labeling and risk assessment purposes.