Registration Dossier
Registration Dossier
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EC number: 685-616-3 | CAS number: 66094-79-9
Endpoint summary
Administrative data
Description of key information
Two acute experimental studies and two QSAR predictions are available to assess the aquatic toxicity of the registered substance.
For aquatic invertebrates, the experimental study, performed on Daphnia magna, was not considered reliable due to major methodological deficiencies. Therefore, a QSAR prediction for this endpoint was performed using iSafeRat® High-Accuracy-Quantitative Structure-Activity Relationship (KREATIS, 2020a) and the 48h-EC50 value, used as key data, was predicted at 88 mg/L.
For algae, the experimental study, performed on Desmodesmus subspicatus, was considered reliable. In this study, the 72h-ErC50 value based on growth rate was greater than 100 mg/L, the limit test concentration. However, in order to obtain a quantitative toxicity value, a QSAR prediction was performed using iSafeRat® High-Accuracy-Quantitative Structure-Activity Relationship (KREATIS, 2020b). The 72h-ErC50 value, used as key data, was predicted at 130 mg/L.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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