Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation, other
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: QSAR report
Title:
Unnamed
Year:
2022

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: QSAR prediction
Deviations:
no
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
tributyl(ethyl)phosphonium 4-methylbenzenesulfonate
Cas Number:
119520-10-4
Molecular formula:
C21H39O3PS
IUPAC Name:
tributyl(ethyl)phosphonium 4-methylbenzenesulfonate

Results and discussion

In vivo (LLNA)

Results
Key result
Parameter:
EC3
Remarks on result:
positive indication of skin sensitisation based on QSAR/QSPR prediction

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
The Skin sensitisation of Tributyl (ethyl) phosphonium ptoluenesulfonate( 1:1) is Positive.
Executive summary:

Predicted endpoint: EC3; No effect specified; No species specified; No duration specified; No guideline
specified
Predicted value: Positive
Unit/scale: Skin Sensitization (Danish EPA)
Data gap filling method: Read-across analysis
Summary: manually editable field
Not provided by the user