Registration Dossier
Registration Dossier
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EC number: 615-247-5 | CAS number: 71060-57-6
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin corrosion: in vitro / ex vivo
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to the category justification provided in the category object.
Data source
Materials and methods
Test material
- Reference substance name:
- Alcohols, C8-10, ethoxylated, < 2.5 EO
- Cas Number:
- 71060-57-6
- Molecular formula:
- C8H17(OC2H4)nOH; n = 1 – 2.5; C10H21(OC2H4)nOH; n = 1 – 2.5 (average)
- IUPAC Name:
- Alcohols, C8-10, ethoxylated, < 2.5 EO
Constituent 1
Results and discussion
In vitro
Resultsopen allclose all
- Irritation / corrosion parameter:
- % tissue viability
- Run / experiment:
- 3 min exposure
- Remarks on result:
- other: Corrosive based on available skin irritation / corrosion data in the Alcohol Ethoxylates (AE) category.
- Irritation / corrosion parameter:
- % tissue viability
- Run / experiment:
- 60 min exposure
- Remarks on result:
- other: Corrosive based on available skin irritation / corrosion data in the Alcohol Ethoxylates (AE) category.
Any other information on results incl. tables
For a detailed assessment of the skin irritation / corrosion potential of the Alcohol Ethoxylates (AE) category, please refer to the category justification attached to the category object.
Applicant's summary and conclusion
- Interpretation of results:
- other: Skin corr. 1, H314. Classification according to Regulation (EC) No. 1272/2008 (CLP/EU GHS).
- Conclusions:
- Applying read-across based on grouping of substances (category approach), skin corrosion is predicted for the target substance.
- Executive summary:
The available data on skin irritation / corrosion in the Alcohol Ethoxylates (AE) category indicate skin corrosion for the target substance. As explained in the category justification, the differences in molecular structure and composition between the target substance and the members of the AE category are unlikely to lead to differences in the skin irritation / corrosion potential.
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