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Diss Factsheets
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EC number: 700-786-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- yes
- Remarks:
- not GLP study
- GLP compliance:
- no
- Remarks:
- The testing lab was not GLP in 2009 but study of good quality (klimisch score 2) so can be used for registration purpose
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- Daphnia magna
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 250mg/l +/- 25 mg (CaCO3)
- Test temperature:
- 20°C +/- 2
- pH:
- 7.8 +/- 0.2
- Dissolved oxygen:
- >7mg/l
- Nominal and measured concentrations:
- Nominal (test item sample): 12.00, 24.15, 48.61, 71.95 and 97.79 mg/L along with a control group without test item.
Nominal (based on 60.6% dry matter content): 7.27, 14.64, 29.46, 43.60 and 59.26 mg/L along with a control group without test item. - Reference substance (positive control):
- yes
- Remarks:
- K2Cr2O7
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 24 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mobility
- Remarks on result:
- other: based on "dry matter" concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 40 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Validity criteria fulfilled:
- yes
- Conclusions:
- CE 50-48h for dry matter is 24 mg/l.
CE 50-48h for raw material is 40 mg/l.
Reference
Description of key information
Commercial samples of the registered substances are typically produced as aqueous solutions. An acute daphnia study was performed on a commercial quality of Sophorolipids (Lot 01/09), which had been determined to contain 60.6% dry matter. The 48h EC50 was determined to be 40mg/L (based on test item) and 24mg/L (based on the dry matter content). The latter has been chosen as the key value as this represents the sophorolipids content in the commercial product.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- 24 mg/L
Additional information
The acute toxicity of the Sophorolipids (60.6% dry matter) to Daphnia magna was determined in a 48h test according to the European Standard ISO 5341 and OECD Guideline 202. Based on the results of a range finding test, a definitive test was conducted at 5 test item concentrations of 12.00, 24.15, 48.61, 71.95 and 97.79 mg/L along with a control group without test item. The test item concentrations are equivalent to 7.27, 14.64, 29.46, 43.60 and 59.26 mg/L based on dry matter.
No cumulative immobilization was observed in the control and 12.00 mg/L test concentration (7.27mg/L based on dry matter), whereas 10, 70, 95 and 100% immobilization was observed in the tested concentrations of 24.15, 48.61, 71.95 and 97.79 mg/L respectively (14.64, 29.46, 43.60 and 59.26 mg/L based on dry matter).
Based on the results of this study, the 48h EC50 value for Sophorolipids was found to be 40mg/L (based on test item) and 24mg/L (based on the dry matter content).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.