Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 41 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.41 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 4.1 µg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
- PNEC marine water (intermittent releases):
- 41 µg/L
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 45 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.22 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 22 µg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 20 µg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Derivation of PNECs
The PNECs for the different compartments are calculated either by application of an assessment factor (PNEC freshwater, PNEC marine water, PNEC intermittent release and PNEC stp) or by using the equilibrium assumption method (PNEC sediment-freshwater, PNEC sediment-marine-water and PNEC soil). The PNEC air is not considered as relevant based on the chemical structure and intrinsic properties of the registered substance. Secondary exposure of mammals and birds is not expected, and since no adequate bird or mammalian data are available, the PNECsecondary poisoning is omitted. The utilized procedures are described in detail in the ECHA REACH Guidance of May 2008, Chapter R.10 ("Characterisation of dose [concentration]-response for environment").
Conclusion on classification
There is no data available for the target substance on toxicity towards aquatic organisms and microorganisms. However, there is data available for the source substances (manganese salts and Fe(Na)EDDHA). With regard to the data for manganese the hazard values were converted to the registered substance under consideration of the maximum percentage of manganese included in the substance. This data is used within the concept of a weight-of-evidence approach to assess the toxicity of the target substance.
According to the LC/EC50 data derived
from OECD guideline studies with the source substance Fe(Na)EDDHA,
representing the organic part of the target substance Mn(Na2)EDDHA,
it can be concluded that no toxicity towards aquatic organisms is
triggered by this compound.
Taking into account the lowest acute LC/EC50 value found in literature
for manganese compounds including MnSO4and MnCl2,
converted to the manganese moiety in the target substance an ERV of =
41.33 mg/L for Selenastrum capricornutum has been derived.
Applying the criteria for classification of soluble metal compounds
specified in the ‘Guidance on the Application of the CLP Criteria’
(version 5.0 – July 2017), Annex IV, classification for acute
environmental toxicity is not needed if the ERV > 1 mg/L. No chronic
data has been provided in the dossier as this is not a requirement under
Annex VIII to REACH Regulation. (In absence of relevant chronic
toxicity data, and unless there is evidence of both rapid environmental
transformation and evidence of no bioaccumulation, readily soluble metal
compounds are classified as Category Chronic 3 if the acute ERV > 10
mg/L and ≤ 100 mg/L.) Nonetheless reliable chronic data is
available according to the disseminated REACH registration dossiers of
MnSO4and MnCl2. The lowest chronic value was
obtained in the brook trout study (Davies & Brinkman 1998*) with MnSO4
of 0.55 mg Mn/L. After correction to the Mn moiety in the target
substance a chronic ERV of 7.3 mg/L can be derived. In cases where both
the acute and chronic ERV are greater than 1 mg/L there is no need to
classify for either acute or chronic effects according to Regulation
(EC) No 1272/2008.
*Davies, P.H. and S.F. Brinkman. 1998. Toxicity of manganese to early-life stage and fry of brook trout (Salvelinus fontinalis) and rainbow trout (Oncrhynchus mykiss) in water hardnesses of 30 and 150 mg/L. Federal Aid in Fish and Wildlife Restoration Job Progress Report, Colorado Division of Wildlife, Fish Research Section.Fort Collins, CO, USA
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)