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Diss Factsheets
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EC number: 617-441-5 | CAS number: 83121-18-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Hydrolysis:
In the key study (BASF DocID: TZ-322-001, 1987) teflubenzuron was found to be stable to hydrolysis at pH 5 and 7 after 30 d at 25°C. At a temperature of 25 °C and a pH of 9 the hydrolsis DT50 of teflubenzuron is 8.7 days . The hydrolysis DT50 of teflubenzuron at pH 9 was calculated to be 24.6 days at 12 °C (Chapter R.7b, p.222: Endpoint specific guidance Version 4.0 – June 2017). The metabolites identified after 30 days at pH 9 were 3,5-dichloro-2,4-difluorophenylurea (61% AR from the aniline label), 3,5-dichloro-2,4-difluoroaniline (12% AR from the aniline label), 2,6-difluorobenzoic acid (62% AR from the benzoyl label), 2,6-difluorobenzamide (12% AR from the benzoyl label), and N-(2,4-difluoro-3,5-dichlorobenzene)-5-fluoro[3H]-dihydroquinazoline-2,4-dione (8% AR from the aniline label and 5% AR from the benzoyl label).
Phototransformation in air:
Following the Atkinson calculation, the photochemical half-life for reactions with OH-radicals (12-hr day; 1.5 x 106 OH/cm3) was determined to be 1.7 days (BASF DocID: TZ-630-013).
Phototransformation in water:
Teflubenzuron was stable to photolysis for up to 7 days (93% AR as teflubenzuron, BASF DocID: TZ-322-002, 1987) at pH 5 and 25 °C. The degradation was then accelerated with 45% AR as teflubenzuron after 15 days. A photolytic half-life was estimated at about 10 days.
Since teflubenzuron was stable for up to 7 days, it was proposed that no aqueous photolysis studies are required on metabolites.
Phototransformation in soil:
In the study of Hawkins (1987, DocID: TZ-620-007) Teflubenzuron was photodegraded with a half-life of about 104 days. The metabolite 3,5-dichloro-2,4-difluorophenylurea appeared after 15 days at a level of 2% AR.
Photodegradation will not be the main degradation route of teflubenzuron in soil.
Additional information
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