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EC number: 221-391-6 | CAS number: 3084-40-0
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Deviations:
- no
- Principles of method if other than guideline:
- n/a
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Diethyl (hydroxymethyl)phosphonate
- EC Number:
- 221-391-6
- EC Name:
- Diethyl (hydroxymethyl)phosphonate
- Cas Number:
- 3084-40-0
- Molecular formula:
- C5H13O4P
- IUPAC Name:
- diethyl (hydroxymethyl)phosphonate
- Test material form:
- other: meduim viscosity liquid
- Details on test material:
- E06-16 (Lot# 1041-37-6, Sample: T# 207), transparent "medium-viscoosity" liquid.
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- < 0.3
- Temp.:
- 25 °C
- Remarks on result:
- other: E06-16 eluted after approximately 2.7 minutes under the conditions of the analysis, compared to a retention time of 3.1 minutes for the reference substance, 2-butanone, which has a known log10Pow value of 0.3.
- Remarks:
- A log10Pow value for E06-16 of less than 0.3 was thus obtained.
- Details on results:
- E06-16 eluted after approximately 2.7 minutes under the conditions of the analysis, compared
to a retention time of 3.1 minutes for the reference substance, 2-butanone, which has a known
log10Pow value of 0.3. A log10Pow value for E06-16 of less than 0.3 was thus obtained.
Any other information on results incl. tables
No further information
Applicant's summary and conclusion
- Conclusions:
- E06-16 was found to have a log10Pow value of less than 0.3 (equivalent Pow < 2).
- Executive summary:
A study was performed to determine the partition coefficient of the test substance, E06-16.
The method followed is amongst those described in Commission Regulation (EC) No.
440/2008 (Method A.8) and the OECD Guidelines for the Testing of Chemicals (Test
Guideline 117).
E06-16 was determined to have a log10Pow value of less than 0.3 (equivalent Pow < 2).
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