Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 250-097-0 | CAS number: 30233-64-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- other: Weight-of-evidence
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- No acute, algae toxicity data is available for the substance. The substance is a mono-glyceride, and based on a WoE approach, where a huge data-set on the acute toxicity of mono-, di- and triglycerides are collected - all showing that the substance is not acutely toxic to algae at concentrations up the the water solubility. Detailed information is given in the attached report.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The substance is a mono-glyceride, and assessment of the acute toxicity to algae is based on a WoE approach using a huge data-set on the acute toxicity of mono-, di- and triglycerides (see attached WoE document for details).
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 0.001 mg/L
- Basis for effect:
- growth rate
- Remarks on result:
- other:
- Remarks:
- based on a WoE approach, it is concluded that the substance is not acutely toxic to algae in concentrations up the water water solubility limit of the substance
- Details on results:
- Based on a WoE approach, it is concluded that the substance is not acutely toxic to algae in concentrations up the water water solubility limit of the substance
- Conclusions:
- The substance is a mono-glyceride, and based on a WoE approach, it is concluded that the substance is not acutely toxic to algae in concentrations up the water water solubility limit of the substance
- Executive summary:
The substance is a mono-glyceride, and based on a WoE approach, it is concluded that the substance is not acutely toxic to algae in concentrations up the water water solubility limit of the substance
Reference
Description of key information
Glycerol monobehenate is a mono constituent substance with a purity of 80-90%. Test data on short-term toxicity to algae are not available for Glycerol monobehenate. The environmental toxicity of this substance was therefore assessed based on a weight of evidence analysis.
A large set of test data on environmental toxicity have been found for the group of mono-, di- and triglycerides and on the environmental toxicity of the hydrolysis products of the substance to constitute a basis for conclusion on short-term toxicity of the substance.
Several test data on the acute toxicity is found on the group of mono-, di- and triglycerides and fatty acids - all concluding that no acute toxicity is shown at concentrations up to the water solubility. Hereby, a huge data set is available for the deriving a conclusion on the acute toxicity of the substance.
Based on the studies available in the present analysis, it is concluded that the compound “Docosanoic acid, monoester with glycerol” is not acutely toxic at concentrations up the water solubility of the substance:EC50(Algae, 72 hr): > water solubility
The available information comprises adequate, reliable studies from reference substances with similar structure and intrinsic properties. The weight-of-Evidence approach is justified based on common functional group and common precursors/breakdown products. The information from these independent sources is consistent and provides sufficient weight of evidence leading to an endpoint conclusion in accordance with Annex XI, 1.2, of Regulation (EC) No 1907/2006.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.