Registration Dossier
Registration Dossier
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EC number: 220-942-8 | CAS number: 2944-06-1
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vitro
- Type of information:
- other: Assessment
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Assessment
Data source
Reference
- Reference Type:
- other: Statement
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 442D (In Vitro Skin Sensitisation: ARE-Nrf2 Luciferase Test Method)
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 442E (In Vitro Skin Sensitisation: Human Cell Line Activation Test (h-CLAT)
- GLP compliance:
- yes
- Type of study:
- activation of dendritic cells
Test material
- Reference substance name:
- Hexadecyl hydrogen maleate
- EC Number:
- 220-942-8
- EC Name:
- Hexadecyl hydrogen maleate
- Cas Number:
- 2944-06-1
- Molecular formula:
- C20H36O4
- IUPAC Name:
- (2Z)-4-(Hexadecyloxy)-4-oxo-2-butenoic acid
Constituent 1
In vitro test system
- Details on the study design:
- Asssessment
Results and discussion
In vitro / in chemico
Results
- Remarks on result:
- not determinable because of methodological limitations
Applicant's summary and conclusion
- Conclusions:
- Asssessment
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