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EC number: 243-424-3 | CAS number: 19910-65-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- other: Research memorandum
- Adequacy of study:
- key study
- Study period:
- Study period: 9 December 1981
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- other: Research memorandum
- Title:
- Unnamed
- Year:
- 1 981
- Report date:
- 1981
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- HPLC method
- GLP compliance:
- not specified
- Type of method:
- other: HPLC method
Test material
- Reference substance name:
- Bis-sec-butyl peroxydicarbonate
- EC Number:
- 243-424-3
- EC Name:
- Bis-sec-butyl peroxydicarbonate
- Cas Number:
- 19910-65-7
- Molecular formula:
- C10H18O6
- IUPAC Name:
- 2-[({[(butan-2-yloxy)carbonyl]peroxy}carbonyl)oxy]butane
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- Samples of the analysed peroxides were supplied by the application laboratory KL-II. Trigonox SBP was stored at -20°c. All peroxides were normal production samples.
Results and discussion
Water solubility
- Key result
- Water solubility:
- 40 other: mg/kg
- Conc. based on:
- test mat.
- Temp.:
- 26 °C
- pH:
- > 0
- Remarks on result:
- other: pH not stated in report
Any other information on results incl. tables
Determination of the detection limit
The detection limits of the peroxides were established before the solubilities were determined. Quantification was carried out by measuring peak heights. Optimum mobile phases were selected for the
peroxides under investigation.
Peroxide |
Assay in % iodometrically |
Mobile phase (vol %) |
Capacity factor |
Detection limit (µg) |
Trigonox SBP bis(sec-butylperoxy) dicarbonate |
98 |
hexane-ethyl acetate 90-10 |
0.69 |
2.7 |
Applicability of the distillation
In the procedure of the determination of the solubility, a vacuum distillation at 0 °C is carried out. An experiment was executed to establish whether the peroxide content was affected by the distillation.
A part of a standard solution in hexane was taken and distilled at about 0 °C. Next the remaining peroxide was dissolved and injected onto the column. Another part of the standard solution was injected directly onto the column and peak heights were compared. For all the peroxides no differences in peak heights were found.
The determination of the solubility of the peroxides in water
Saturated solutions of the peroxide in water were obtained. The mixture was stirred for one, three and six hours respectively. This was done because the solubility depends to some extent on the
stirring time.
An aliquot of 25 ml of the clear water layer was taken and afterwards dissolved in 10 ml mobile phase. In this way a concentration step of 2.5 times was obtained. This is important when the solubility of a peroxide is very low.
Peroxide |
Amount of peroxide (g) |
Amount of water (g) |
Stirring time (h) |
Solubility (mg/kg) |
Trigonox SBP |
2.129 |
39.611 |
1 |
44 |
2.087 |
37.965 |
3 |
34 |
|
2.134 |
38.017 |
6 |
38 |
Applicant's summary and conclusion
- Conclusions:
- Conclusions
1. HPLC-methods to determine each peroxide were developed. The lower limits of detection were established.
2. No loss of peroxide was found during the hexane distillation for each peroxide under investigation.
3. The solubility of Trigonox SBP was about 40 mg/kg. - Executive summary:
The peroxides were dissolved in water at about 0 °C, until a saturated solution was obtained. The excess peroxide was removed by filtration. An aliquot of the clear water layer was extracted with hexane. The hexane was distilled at about 0 °C under vacuum and the remaining peroxide was dissolved in the mobile phase. The composition of this mobile phase was optimised for each peroxide to get the lowest detection limit.
With the developed HPLC method the peroxide content was determined and the solubility in water calculated.
The solubility of Trigonox SBP was about 40 mg/kg.
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