Potassium isobutyrate

Auto flammability

Link to relevant study record(s)

Reference

Endpoint:

relative self-ignition temperature (solids)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

21 - 22 March 2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.16 (Relative Self-Ignition Temperature for Solids)

Deviations:

yes

Remarks:

The heating rate slightly deviated from the value stated in the guideline of 0.5 °C/min (0.58 °C/min). This is considered as uncritical as a nominal heating rate of 0.5 °C/min was adjusted at the instrument and only a minimal deviation was observed.

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Sponsor / 181101001
- Expiration date of the lot/batch: 31 Oct 2020
- Purity test date: 01 Nov 2018

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: The test item was stored in the test facility in a tightly closed vessel at room temperature (16.2 – 23.7 °C) away from humidity.
- Stability under test conditions: Stable
- Solubility and stability of the test substance in the solvent/vehicle:
Stability: H2O: 96h; EtOH: unknown; acetone: unknown; CH3CN: unknown; DMSO: unknown
Solubility: H2O: > 1 g/L; EtOH: unknown; acetone: unknown; CH3CN: unknown; DMSO: unknown

Key result

Relative self-ignition temperature:

397.7 °C

Weight of cube

Weight (test item)	Weight (cube + Test Item)
3.6234g	7.3767g

 

 Temperature Data

The temperatures which were measured in the experiment are presented in the following table. As many values were recorded, only the values every 60 minutes (until the oven had has stopped automatically) are presented.

 Presentation of Temperatures versus Time

Time in min	Temperature (test item) in °C	Temperature (oven) in °C
5 Start	22.8	21.9
60	38.1	49.0
120	69.6	83.2
180	103.0	117.7
240	136.6	155.8
300	172.4	190.8
360	208.8	227.1
420	246.9	263.7
480	319.8	299.1
540	333.0	334.5
600	370.9	368.7
649 End	400.0	397.7

Conclusions:

An increase in the temperature of the sample in comparison to that of the oven could be detected; also signs of ignition could be observed.
The test item Potassium isobutyrate is considered as auto-flammable with a Relative Self Ignition Temperature of 397.7 °C under the test conditions.

No observations were made which might cause doubts concerning the validity of the study outcome.

Executive summary:

Title of Study:                                              Determination of the Relative Self Ignition Temperature of Potassium isobutyrate according to EU-Method A.16

 

 Findings and Results:

 

 

The self ignition temperature of Potassium isobutyrate was determined by placing the test item into a stainless steel cube and heating from room temperature to an oven temperature of 397.7°C with the ZPA-3 oven. The nominal oven temperature was adjusted to 400°C. As the Self Ignition at the temperature of 397.7°C was detected, the ZPA3 was stopped automatically.

An increase in the temperature of the sample in comparison to that of the oven was detected, also signs of ignition were observed.

Therefore, the test item Potassium isobutyrate should be considered as:

Auto-flammable

With a Relative Self Ignition Temperature of 397.7°C

Description of key information

One key study performed in accordance with EU Method A.16 and under the conditions of GLP.

Key value for chemical safety assessment

Autoflammability / Self-ignition temperature at 101 325 Pa:

397.7 °C