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EC number: 268-776-5 | CAS number: 68140-14-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Imidazoline DETA
Alkyl polyethylene amine imidazolines are for the main fraction protonated under ambient conditions. This means that they will sorb strongly to negatively charged surfaces like glassware, soil and sediment constituents. For both DETA based Imidazoline, Kd values were observed ranging from: 19000 to 170000 L/kg for three different types of soil.
Hydrolysis in combination with biodegradation is considered to be the main removal mechanism of these substances. The DETA based amidoamine/imidazolines is completely metabolized to CO2, H2O and NO3.
The half-life in the different environmental compartments may be influenced by the bioavailability of the substances. No data is available for the determination of the half-life of alkyl amidoamines/imidazolines in soil or sediment. For risk assessment purposes, these values are estimated based on the inherent biodegradability of the available fraction and the sorption data as determined in a sorption desorption test. These environmental half-life's should be considered as worst-case values and are not considered to be a realistic reflection of reality.
The Table below summarizes half-lives derived through default values and a simulation study.
Eco(system) | Method | |
Surface water (fresh) | TGD default value | 150 days half life |
Surface water (fresh) sediment | TGD default value | 300000 days half life |
Marine water | TGD default value | 500000 days half life |
Marine water sediment | TGD default value | 300000 days half life |
Soil | TGD default value | 300000 days half life(a) |
(a)Half-life of the fraction dissolved in the water phase is expected to in the order of a few days.
Alkyl amidoamines/imidazolines have a short predicted half-life in air but because there are no important releases into the atmosphere and volatilisation is expected to be negligible, this removal mechanism is thought to be of low relevance.
Alkyl amidoamines/imidazolines contain hydrolysable covalent bonds and the rate of hydrolysis was measured for a TEPA based imidazoline. Cleavage of a carbon-nitrogen bond under environmental conditions is only possible with a carbonyl group adjacent to the nitrogen atom.
Direct photolysis of Alkyl amidoamines/imidazolines in air/water/soil will most likely not occur, because it does not absorb UV radiation above 290 nm. Photo transformation in air/water/soil is therefore assumed to be negligible. Daylight might however influence the rate of hydrolysis.
Standard OECD 305 tests are technically not feasible with these strongly sorbing degradable substances. In addition is the route of exposure in a standard OECD 305 test unrealistic for these substances because the substance will either be sorbed or degraded. The bioaccumulation potential of amidoamines/imidazolines was therefore assessed based on a measured log Kow. As indicated before, imidazolines are quickly hydrolyzed and consequently biodegraded and it is therefore unlikely that they will accumulate in the food chain. The log Kow value as observed for the DETA based imidazoline can be considered as a worst-case as low log Kow values are expected for a higher number of amines in the structure. Based on this log Kow value of 2.2, the calculated log BCF is 1.24 (BCF = 17.4; EpiSuite v4.0).
Rosins
Several reliable biodegradation studies are available for members of this category, for rosin and for monovalent and divalent salts of rosin. Based on the results of these studies, members of the category Rosin, hydrogenated rosin and their salts would be considered readily biodegradable.
Information on accumulation in aquatic organisms is vital for understanding the environmental behaviour of a substance. Accumulation is a general term for the net result of absorption (uptake), distribution, metabolism and excretion (ADME) of a substance in an organism.
A study is available with measured BCF values for various rosin acids. Rosin acids are the predominant components of rosin. Therefore it is considered appropriate to read across from rosin acids. Rainbow trout (Oncorhynchus mykiss) were exposed to nine resin acids that included abietic, dehydroabietic, chlorodehydroabietic, dichlorodehydroabietic, neoabietic, pimaric, isopimaric, sandaracopimaric, and palustric acids. Bioconcentration factors (BCFs) for these acids ranged from <25 to 130 among fish that were exposed to mean waterborne concentrations of 0.7 to 3.6 ug/L for 20 days. Total free and conjugated acid concentrations ranged from 1 to 3 mg/kg on a whole body basis. Elimination rates were also monitored over a 10-day depuration period, although no detectable levels were observed. Based on initial chemical concentrations, it was concluded that the half-lives of these acids were < 4 days. QSAR estimation using the BCFBAF v3.00 of the EPISUITE 4.0 indicate that the calculated BCF values for members of the Rosin, hydrogenated rosin and their salts category are below the B criteria of 2000 L/kg.
Based on the environmental properties of the compounds, where possible worst case values were chosen for the risk assessment. The substance was concluded to be inherently biodegradable based on the Imidazoline DETA data as this represented the worst case. A BCF of 130 L/kg was chosen for the risk assessment based on the rosins data is this was considerd to represent the worst case. Rather than select a Koc for the individual substances, the Koc for use in the risk assessment will be derived from an experimentally derived Kow for Tall oil reaction products with diethylenetriamine.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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