Registration Dossier
Registration Dossier
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EC number: 237-424-2 | CAS number: 13780-06-8
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 23 January - 9 March 2018 [several physical-chemical studies]
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- Good quality study, conducted to GLP. The reporting deficiencies are not expected to influence the validity of the result.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- The pH was not reported.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- The pH was not reported.
- GLP compliance:
- yes
- Type of method:
- other: gravimetric procedure based on the results of a preliminary test
- Water solubility:
- > 500 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- Remarks on result:
- other: The pH was not reported.
- Details on results:
- Addition of 2 mL purified water to approximately 2 g of test item resulted in 96.02 and 96.05% solubles in the two respective replicates. The solubility was therefore confirmed to exceed 500 g/L. No further testing was considered necessary.
- Conclusions:
- In a guideline GLP study, the water solubility of anhydrous calcium nitrite was determined to exceed 500 g/L (i.e. highly soluble).
- Executive summary:
In an OECD guideline study (TG 105), conducted according to GLP, the water solubility of anhydrous calcium nitrite (estimated in a preliminary test and subsequently confirmed by gravimetric analysis conducted in duplicate) was determined to be greater than 500 g/L. As such, calcium nitrite is considered to be highly soluble.
Reference
Description of key information
In an OECD guideline study (TG 105), conducted according to GLP, the water solubility of anhydrous calcium nitrite (estimated in a preliminary test and subsequently confirmed by gravimetric analysis conducted in duplicate) was determined to be greater than 500 g/L at room temperature (approximately 20 °C) (Sydney, 2018). As such, calcium nitrite is considered to be highly soluble.
Key value for chemical safety assessment
- Water solubility:
- 500 g/L
- at the temperature of:
- 20 °C
Additional information
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