Registration Dossier
Registration Dossier
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EC number: 201-946-9 | CAS number: 89-86-1
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 09.04.2018 - 13.04.2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- Published in O.J. L 142, 2008
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
Test material
- Reference substance name:
- 2,4-dihydroxybenzoic acid
- EC Number:
- 201-946-9
- EC Name:
- 2,4-dihydroxybenzoic acid
- Cas Number:
- 89-86-1
- Molecular formula:
- C7H6O4
- IUPAC Name:
- 2,4-dihydroxybenzoic acid
- Test material form:
- solid
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- 5.96 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- >= 2.42 - <= 2.47
Any other information on results incl. tables
Table: Results of determination of test substance solubility in water by flask method
Day |
pH of saturated solution |
1stinjection (mg/L) |
2ndinjection (mg/L) |
Average of 1stand 2ndinjection (mg/L) |
1st |
2.47 |
6.04 |
6.04 |
6.04 |
2nd |
2.42 |
5.88 |
5.88 |
5.88 |
3rd |
2.42 |
5.96 |
5.95 |
5.96 |
Mean |
5.96 |
|||
SD |
0.08 |
|||
RSD (%) |
1.35 |
|||
Repeatability of measurement is less than 15 %, the individual results may be averaged.
Applicant's summary and conclusion
- Conclusions:
- The water solubility of the test substance 2.4-Dihydroxybenzoic acid determined by the flask method is 5.96 g/L.
- Executive summary:
The water solubility of beta-resorcylic acid acc. to EU-method A.6 is 5.96 g/L.
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