Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 211-506-8 | CAS number: 654-62-6
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Endpoint conclusion
- Endpoint conclusion:
- no study available
Genetic toxicity in vivo
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Germ cell mutagenicity
Experimental data on the potential of germ cell mutagenicity of 2,4-Disulfamyl-5-TMSA are not available.
QSAR Toolbox has identified structural alerts for this property: (i) H-acceptor-path3-H-acceptor, (ii) Primary aromatic amine, hydroxyl amine and its
derived esters. In order to estimates in vitro mutagenicity from physicochemical property ranges and structural rules, the software Toxtree has been used and the substance has been predicted as "Unlikely to be a S. typhimurium TA100 mutagen". Moreover, the Danish QSAR database contains
prediction on in vivo genotoxicity and in vitro genotoxicity that are considered as inconclusive.
Overall, available information are judged as inconclusive for the classification of the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
